Gene Symbol | LIPI |
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Entrez Gene | 149998 |
Alt Symbol | CT17, LPDL, PLA1C, PRED5, mPA-PLA1 beta |
Species | Human |
Gene Type | protein-coding |
Description | lipase, member I |
Other Description | LPD lipase|cancer/testis antigen 17|lipase member I|membrane-associated phosphatidic acid-selective phospholipase A1-beta |
Swissprots | Q6XZB0 G1JSG4 G1JSG6 G1JSG8 G1JSG7 G1JSG9 G1JSG3 G1JSG5 |
Accessions | Q6XZB0 AI017218 AY197607 AAP37476 AY918476 AAX14040 BC140336 AAI40337 BC148691 AAI48692 BI460152 JN387910 AEL12688 JN387911 AEL12689 JN387912 AEL12690 JN387913 AEL12691 JN387914 AEL12692 JN387915 AEL12693 JN387916 AEL12694 XM_006723965 XP_006724028 XM_006723966 XP_006724029 NM_001302998 NP_001289927 NM_001302999 NP_001289928 NM_001303000 NP_001289929 NM_001303001 NP_001289930 NM_198996 NP_945347 NM_145317 |
Function | Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). {ECO:0000269|PubMed:12963729}. |
Subcellular Location | Isoform 1: Membrane. Secreted. Note=May associate with lipid draft. |
Tissue Specificity | Expressed in testis. Expressed exclusively at the connecting piece of the sperm. {ECO:0000269|PubMed:12719377, ECO:0000269|PubMed:12963729}. |
LPD lipase (T-17) - sc-54087 from Santa Cruz Biotechnology
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Anti-LIPI antibody - ab202348 from Abcam
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Anti-LIPI antibody - ab106123 from Abcam
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Anti-LIPI antibody - ab168208 from Abcam
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Anti-LIPI Antibody - LS-C295156 from LifeSpan Bioscience
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Anti-LIPI Antibody (aa272-321) - LS-C292140 from LifeSpan Bioscience
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Anti-LIPI Antibody (FITC) - LS-C303127 from LifeSpan Bioscience
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Anti-LIPI Antibody (Biotin) - LS-C305826 from LifeSpan Bioscience
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Anti-LIPI Antibody (aa289-338) - LS-C120064 from LifeSpan Bioscience
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Anti-LIPI Antibody (aa359-408) - LS-C111075 from LifeSpan Bioscience
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Anti-LIPI Antibody (aa224-258) - LS-C344467 from LifeSpan Bioscience
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Lipase I Antibody - AF5909 from Novus Biologicals
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Lipase I Antibody - NBP1-56620 from Novus Biologicals
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Lipase I Antibody - H00149998-B01 from Novus Biologicals
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Lipase I Antibody - NBP1-85412 from Novus Biologicals
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Lipase I Antibody - H00149998-B01P from Novus Biologicals
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Anti-LIPI antibody produced in rabbit - SAB2105657 from Sigma-Aldrich
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Anti-LIPI antibody produced in rabbit - HPA029950 from Sigma-Aldrich
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Anti-LIPI antibody produced in rabbit - SAB4500547 from Sigma-Aldrich
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LIPI antibody - middle region (ARP45940_P050) - ARP45940_P050 from Aviva Systems Biology
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LIPI-Antibody-Center - AP20877a from Abgent, a WuXi AppTec company
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LIPI-Antibody-Center - AP21120a from Abgent, a WuXi AppTec company
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LIPI antibody - GTX87435 from GeneTex
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Human Lipase I Antibody - AF5909 from R&D Systems
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Human Lipase I Affinity Purified Polyclonal Ab, Goat IgG - AF5909-SP from R&D Systems
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