Gene Symbol | EFHD2 |
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Entrez Gene | 79180 |
Alt Symbol | SWS1 |
Species | Human |
Gene Type | protein-coding |
Description | EF-hand domain family, member D2 |
Other Description | EF hand domain containing 2|EF hand domain family, member D2|EF-hand domain-containing protein D2|swiprosin 1|swiprosin-1 |
Swissprots | Q5JYW9 Q96C19 |
Accessions | EAW51720 EAW51721 EAW51722 EAW51723 Q96C19 AI624416 BC003033 BC007233 AAH07233 BC013648 BC014923 AAH14923 BC023611 AAH23611 BC068473 AAH68473 BI753983 BM796344 XM_005246000 XP_005246057 XM_011542114 XP_011540416 NM_024329 NP_077305 |
Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. {ECO:0000250}. |
Subcellular Location | Membrane raft {ECO:0000250}. Note=In a mouse immature B-cell line WEHI-231. {ECO:0000250}. |
Tissue Specificity | Found in lymphocytes; preferentially expressed in CD8+ cells. {ECO:0000269|PubMed:11788997, ECO:0000269|PubMed:15274114}. |
Swiprosin-1 (H-40) - sc-292051 from Santa Cruz Biotechnology
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Swiprosin-1 (A-13) - sc-162276 from Santa Cruz Biotechnology
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Anti-EFHD2 antibody - ab24368 from Abcam
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Anti-EFHD2 antibody - ab106667 from Abcam
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Anti-EFHD2 antibody - ab87006 from Abcam
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Anti-EFHD2 antibody - ab155530 from Abcam
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Anti-EFHD2 antibody - ab155505 from Abcam
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Anti-EFHD2 antibody - ab119119 from Abcam
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Anti-EFHD2 antibody [78.3_6D12] - ab128063 from Abcam
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Anti-EFHD2 Antibody (N-Terminus) - LS-C102809 from LifeSpan Bioscience
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Anti-EFHD2 Antibody (aa230-240) - LS-C55545 from LifeSpan Bioscience
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Anti-EFHD2 Antibody (N-Terminus) IHC-plus⢠- LS-B4639 from LifeSpan Bioscience
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EFHD2 Antibody - NB100-1477 from Novus Biologicals
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EFHD2 Antibody - NBP1-77135 from Novus Biologicals
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EFHD2 Antibody - NBP1-31134 from Novus Biologicals
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Anti-Swiprosin 1/EFHD2 antibody produced in goat - SAB2501007 from Sigma-Aldrich
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Anti-EFHD2, (N-terminal) antibody produced in rabbit - SAB2103306 from Sigma-Aldrich
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Anti-EFHD2 antibody produced in rabbit - HPA048961 from Sigma-Aldrich
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Anti-EFHD2 antibody produced in rabbit - SAB3500166 from Sigma-Aldrich
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EFHD2 antibody - N-terminal region (ARP58617_P050) - ARP58617_P050 from Aviva Systems Biology
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Swiprosin-1--EFHD2-Antibody - AF2054a from Abgent, a WuXi AppTec company
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EFHD2 antibody - GTX108080 from GeneTex
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EFHD2 antibody - orb75383 from Biorbyt
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Goat Anti-Swiprosin 1 / EFHD2 Antibody (OAEB02371) - OAEB02371 from Aviva Systems Biology
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EFHD2 antibody - 70R-17011 from Fitzgerald
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