| Gene Symbol |
DEGS1
|
| Entrez Gene |
8560
|
| Alt Symbol |
DEGS, DEGS-1, DES1, Des-1, FADS7, MIG15, MLD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
delta(4)-desaturase, sphingolipid 1
|
| Other Description |
cell migration-inducing gene 15 protein|degenerative spermatocyte homolog 1, lipid desaturase|degenerative spermatocyte homolog, lipid desaturase|dihydroceramide desaturase 1|membrane fatty acid (lipid) desaturase|membrane lipid desaturase|migration-inducing gene 15 protein|sphingolipid delta 4 desaturase|sphingolipid delta(4)-desaturase 1|sphingolipid delta(4)-desaturase DES1
|
| Swissprots |
O15121
|
| Accessions |
EAW69711 EAW69712 O15121 AB362580 BAF81544 AF002668 AAB62238 AF466375 AAM12531 AK308232 AU126996 AY423730 AAS00493 BC000961 AAH00961 HQ447864 ADQ32348 XM_011544317 XP_011542619 XM_011544318 XP_011542620 NM_144780 NM_003676 NP_003667
|
| Function |
Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). {ECO:0000269|PubMed:11937514}.
|
| Subcellular Location |
Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:9188692}.
|
| Top Pathways |
Sphingolipid signaling pathway, Sphingolipid metabolism
|