DEGS1

Gene Symbol DEGS1
Entrez Gene 8560
Alt Symbol DEGS, DEGS-1, DES1, Des-1, FADS7, MIG15, MLD
Species Human
Gene Type protein-coding
Description delta(4)-desaturase, sphingolipid 1
Other Description cell migration-inducing gene 15 protein|degenerative spermatocyte homolog 1, lipid desaturase|degenerative spermatocyte homolog, lipid desaturase|dihydroceramide desaturase 1|membrane fatty acid (lipid) desaturase|membrane lipid desaturase|migration-inducing gene 15 protein|sphingolipid delta 4 desaturase|sphingolipid delta(4)-desaturase 1|sphingolipid delta(4)-desaturase DES1
Swissprots O15121
Accessions EAW69711 EAW69712 O15121 AB362580 BAF81544 AF002668 AAB62238 AF466375 AAM12531 AK308232 AU126996 AY423730 AAS00493 BC000961 AAH00961 HQ447864 ADQ32348 XM_011544317 XP_011542619 XM_011544318 XP_011542620 NM_144780 NM_003676 NP_003667
Function Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). {ECO:0000269|PubMed:11937514}.
Subcellular Location Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:9188692}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

Degs1 (S-12) - sc-162734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FADS7 (NB-B10) - sc-134338 from Santa Cruz Biotechnology

Prices $295.00
Sizes 200 µl ascites
Host Mouse
Clonality Monoclonal
FADS7 (NB-B10): sc-134338. Western blot analysis of FADS7 expression in Hep G2 whole cell lysate.

Anti-DEGS1 antibody - ab129332 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DEGS1 antibody (ab129332) at 1/100 dilution + T47D cell line lysate at 35 µg

Anti-DEGS1 antibody [EPR9680] - ab185237 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9680
All lanes : Anti-DEGS1 antibody [EPR9680] (ab185237) at 1/10000 dilutionLane 1 : U87-MG cell lysateLane 2 : 293 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-DEGS1 antibody [EPR9681] - ab167169 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9681
All lanes : Anti-DEGS1 antibody [EPR9681] (ab167169) at 1/1000 dilutionLane 1 : 293T cell lysatesLane 2 : T47D cell lysatesLane 3 : HepG2 cell lysatesLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-DEGS1 Antibody (aa1-30) - LS-C167352 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DEGS1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cerebellum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DEGS1 Antibody (N-Terminus) IHC-plus™ - LS-B10879 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Skin: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-DEGS1 Antibody - LS-C140574 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody (aa1-30, AP) - LS-C256011 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody (aa1-30, APC) - LS-C256012 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody - LS-C140626 from LifeSpan Bioscience

Prices $460.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal
IHC of normal human brain tissue using DEGS1 antibody (LS-C140626) at 15 ug/ml.

Anti-DEGS1 Antibody (aa1-30, Biotin) - LS-C256013 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody (aa1-30, FITC) - LS-C256014 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody (aa1-30, Azide-free, HRP) - LS-C256015 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody (aa1-30, PE) - LS-C256016 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DEGS1 Antibody (aa1-30) - LS-C320802 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DEGS1 Antibody - NBP1-59941 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DEGS1 Antibody - NBP1-84279 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DEGS1 Antibody [NBP1-84279] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418506)

DEGS1 Antibody (3F9) - H00008560-M01A from Novus Biologicals

Prices $359.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3F9
Western Blot: DEGS1 Antibody (3F9) [H00008560-M01A] - DEGS1 monoclonal antibody (M01A), clone 3F9. Analysis of DEGS1 expression in HepG2.

DEGS1 Antibody (2E9.) - H00008560-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E9.

Anti-DEGS1 antibody produced in rabbit - SAB2100559 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DEGS1: <B>Cat. No.SAB2100559</B>: DEGS1 in Fetal Muscle tissue lysate with DEGS1 antibody at 1.0 μg/mL.

Monoclonal Anti-DEGS1 antibody produced in mouse - WH0008560M4 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E9

Anti-DEGS1 antibody produced in rabbit - HPA014763 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DEGS1: <B>Cat. No. HPA014763</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebellum shows moderate cytoplasmic positivity in purkinje cells.

Monoclonal Anti-DEGS1, (C-terminal) antibody produced in mouse - SAB1404600 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3F9
<B>Immunoblotting</B><BR/>Monoclonal Anti-DEGS1: <B>Cat. No. SAB1404600</B>: Antibody concentration: 1/500x dilution. Specific band of ~37.9 kDa using HepG2 lysate.

DEGS1 antibody - N-terminal region (ARP45501_P050) - ARP45501_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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