DEGS1

Gene Symbol DEGS1
Entrez Gene 8560
Alt Symbol DEGS, DEGS-1, DES1, Des-1, FADS7, MIG15, MLD
Species Human
Gene Type protein-coding
Description delta(4)-desaturase, sphingolipid 1
Other Description cell migration-inducing gene 15 protein|degenerative spermatocyte homolog 1, lipid desaturase|degenerative spermatocyte homolog, lipid desaturase|dihydroceramide desaturase 1|membrane fatty acid (lipid) desaturase|membrane lipid desaturase|migration-inducing gene 15 protein|sphingolipid delta 4 desaturase|sphingolipid delta(4)-desaturase 1|sphingolipid delta(4)-desaturase DES1
Swissprots O15121
Accessions EAW69711 EAW69712 O15121 AB362580 BAF81544 AF002668 AAB62238 AF466375 AAM12531 AK308232 AU126996 AY423730 AAS00493 BC000961 AAH00961 HQ447864 ADQ32348 XM_011544317 XP_011542619 XM_011544318 XP_011542620 NM_144780 NM_003676 NP_003667
Function Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). {ECO:0000269|PubMed:11937514}.
Subcellular Location Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:9188692}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

FADS7 CRISPR/Cas9 KO Plasmid (h) - sc-406592 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 HDR Plasmid (h) - sc-406592-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 Double Nickase Plasmid (h) - sc-406592-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 Double Nickase Plasmid (h2) - sc-406592-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 CRISPR Activation Plasmid (h) - sc-406592-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 CRISPR Activation Plasmid (h2) - sc-406592-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 Lentiviral Activation Particles (h) - sc-406592-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 Lentiviral Activation Particles (h2) - sc-406592-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 siRNA (h) - sc-78658 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FADS7 shRNA Plasmid (h) - sc-78658-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FADS7 shRNA (h) Lentiviral Particles - sc-78658-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DEGS1 RNAi - H00008560-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU087091 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7131 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7131 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07592 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07592

DEGS1 siRNA (Human) - CRH5629 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DEGS1 RNAi - H00008560-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

DEGS1 - MBS8226166 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FADS7 CRISPR/Cas9 KO Plasmid (h2) - sc-406592-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADS7 HDR Plasmid (h2) - sc-406592-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human DEGS1 (NM_003676.3) - SHH276957 from Creative biogene

Category siRNA
Species Reactivities Human

Human DEGS1 siRNA - orb266131 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DEGS1 shRNA Plasmid (Human) - CHH5629 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DEGS1 miRNA 3'UTR clone - MiUTR3H-14631 from Creative biogene

Species Reactivities Human
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