Gene Symbol | MTNR1A |
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Entrez Gene | 4543 |
Alt Symbol | MEL-1A-R, MT1 |
Species | Human |
Gene Type | protein-coding |
Description | melatonin receptor 1A |
Other Description | mel1a receptor|melatonin receptor type 1A |
Swissprots | A0AVC5 P48039 B0M0L2 |
Accessions | BAA85303 EAX04617 P48039 AF435588 AAL30809 BC074946 AAH74946 BC074947 AAH74947 BC113816 AAI13817 BC126297 AAI26298 BC126299 AAI26300 EU432127 ABY87926 HQ258378 ADR83132 U14108 AAB17720 XM_011532002 XP_011530304 NM_005958 NP_005949 |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus. |
Top Pathways | Circadian entrainment, Neuroactive ligand-receptor interaction |
MEL-1A-R (B-10) - sc-390328 from Santa Cruz Biotechnology
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MEL-1A-R (N-20) - sc-13179 from Santa Cruz Biotechnology
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MEL-1A-R (R-18) - sc-13186 from Santa Cruz Biotechnology
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MEL-1A-R (V-15) - sc-13180 from Santa Cruz Biotechnology
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MEL-1A/B-R (H-120) - sc-30017 from Santa Cruz Biotechnology
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Anti-Melatonin Receptor 1A antibody - ab87639 from Abcam
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Anti-Melatonin Receptor 1A antibody - ab176178 from Abcam
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Anti-Melatonin Receptor 1A antibody - ab184013 from Abcam
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa209-238, AP) - LS-C263697 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa209-238, Biotin) - LS-C263699 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa209-238, APC) - LS-C263698 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa191-240) - LS-C120749 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa209-238, FITC) - LS-C263700 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa209-238, Azide-free, HRP) - LS-C263701 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa209-238, PE) - LS-C263703 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (C-Terminus) - LS-C145401 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa296-350) - LS-C295343 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa312-366, Biotin) - LS-C299749 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa216-257, Biotin) - LS-C300905 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa296-350, Biotin) - LS-C300906 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa300-353, Biotin) - LS-C300907 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa203-229) - LS-C164670 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa312-366, FITC) - LS-C303955 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (aa132-144) - LS-C112831 from LifeSpan Bioscience
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Anti-MTNR1A / Melatonin Receptor 1a Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A216 from LifeSpan Bioscience
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