MTNR1A

Gene Symbol	MTNR1A
Entrez Gene	4543
Alt Symbol	MEL-1A-R, MT1
Species	Human
Gene Type	protein-coding
Description	melatonin receptor 1A
Other Description	mel1a receptor|melatonin receptor type 1A
Swissprots	A0AVC5 P48039 B0M0L2
Accessions	BAA85303 EAX04617 P48039 AF435588 AAL30809 BC074946 AAH74946 BC074947 AAH74947 BC113816 AAI13817 BC126297 AAI26298 BC126299 AAI26300 EU432127 ABY87926 HQ258378 ADR83132 U14108 AAB17720 XM_011532002 XP_011530304 NM_005958 NP_005949
Function	High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.
Top Pathways	Circadian entrainment, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MEL-1A-R CRISPR/Cas9 KO Plasmid (h) - sc-401075 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R HDR Plasmid (h) - sc-401075-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R Double Nickase Plasmid (h) - sc-401075-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R Double Nickase Plasmid (h2) - sc-401075-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R CRISPR Activation Plasmid (h) - sc-401075-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R CRISPR Activation Plasmid (h2) - sc-401075-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R Lentiviral Activation Particles (h) - sc-401075-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R Lentiviral Activation Particles (h2) - sc-401075-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEL-1A-R siRNA (h) - sc-35917 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEL-1A-R shRNA Plasmid (h) - sc-35917-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEL-1A-R shRNA (h) Lentiviral Particles - sc-35917-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Melatonin R1A/MT1/MTNR1A RNAi - H00004543-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU012821 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14725 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14725 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MTNR1A siRNA (Human) - CRH3013 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human MTNR1A (NM_005958.3) - SHH346568 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MTNR1A(NM_005958.3) - SHH207137 from Creative biogene Category siRNA Species Reactivities Human

Human MTNR1A siRNA - orb263515 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MTNR1A shRNA Plasmid (Human) - CHH3013 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MTNR1A miRNA 3'UTR clone - MiUTR1H-06520 from Creative biogene Species Reactivities Human

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