STAT5A

Gene Symbol STAT5A
Entrez Gene 6776
Alt Symbol MGF, STAT5
Species Human
Gene Type protein-coding
Description signal transducer and activator of transcription 5A
Other Description -
Swissprots Q1KLZ6 P42229
Accessions CAD19637 CAG32953 CBX53841 EAW60819 P42229 AB208972 BAD92209 AK291650 BAF84339 AK301457 BAH13486 AK310632 AK310713 BC027036 AAH27036 DQ471288 ABF17939 DQ891723 ABM82649 DQ894900 ABM85826 L41142 AAA73962 U43185 AAB06589 XM_005257624 XP_005257681 NM_001288718 NP_001275647 NM_001288719 NP_001275648 NM_001288720 NP_001275649 NM_003152 NP_003143
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. {ECO:0000269|PubMed:11773439, ECO:0000269|PubMed:15534001}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15534001}. Nucleus {ECO:0000269|PubMed:15534001}. Note=Translocated into the nucleus in response to phosphorylation.
Top Pathways HTLV-I infection, Prolactin signaling pathway, Viral carcinogenesis, Measles, Jak-STAT signaling pathway

Phospho-Stat5 (Tyr694) (D47E7) XP ® Rabbit mAb (PE Conjugate) - 14603 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D47E7
Flow cytometric analysis of TF-1 cells, untreated (blue) or treated with Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF) #8922 (green), using Phospho-Stat5 (Tyr694) (D47E7) XP ® Rabbit mAb (PE Conjugate).

Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (Alexa Fluor ® 647 Conjugate) - 9365 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone C71E5
Flow cytometric analysis of TF-1 cells, untreated (blue) or treated with GM-CSF (green), using Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (Alexa Fluor ® 647 Conjugate).

Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (PE Conjugate) - 5387 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone C71E5
Flow cytometric analysis of TF-1 cells, untreated (blue) or treated with hGM-CSF #8922 (green), using Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (PE Conjugate).

Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (Alexa Fluor ® 488 Conjugate) - 3939 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone C71E5
Flow cytometric analysis of TF-1 cells, untreated (blue) or treated with GM-CSF (green), using Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (Alexa Fluor ® 488 Conjugate).

Stat5 (3H7) Rabbit mAb (Biotinylated) - 4459 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 3H7
Western blot analysis of extracts from HeLa and UT7 cells using Stat5 (3H7) Rabbit mAb (Biotinylated).

Phospho-Stat5 (Tyr694) (D47E7) XP ® Rabbit mAb - 4322 from Cell Signaling Technology

Prices $119.00, $318.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D47E7
Western blot analysis of extracts from UT-7 cells, untreated or treated with erythropoietin (EPO; 3 units/ml for 5 min), TF-1 cells, untreated or treated with Human Granulocyte Macrophage Colony Stimulating Factor #8922 (hGM-CSF; 100 ng/ml for 10 min), and NK-92 cells, untreated or treated with Human Interleukin-2 #8907 (hIL-2; 100 ng/ml for 10 min), using Phospho-Stat5 (Tyr694) (D47E7) XP ® Rabbit mAb.

PhosphoPlus ® Stat5 (Tyr694) Antibody Kit - 9350 from Cell Signaling Technology

Prices $489.00
Sizes 1 kit (10 western blots)
Clonality Polyclonal

Phospho-Stat5 (Tyr694) Antibody - 9351 from Cell Signaling Technology

Prices $287.00, $678.00
Sizes 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from TF-1 cells, treated with GM-CSF (25 ng/ml) for the indicated times, using Phospho-Stat5 (Tyr694) Antibody (upper) or Stat5 antibody (lower).

Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb - 9314 from Cell Signaling Technology

Prices $297.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C71E5
Western blot analysis of extracts from K562, untreated or treated with Gleevec for 1 hour, using Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb (upper) or Stat5 Antibody #9310 (lower).

Phospho-Stat5 (Tyr694) (14H2) Mouse mAb - 9356 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 14H2
Western blot analysis of extracts from K562 and TF-1 cells, untreated, STI571-treated or GM-CSF-treated as indicated, using Phospho-Stat5 (Tyr694) (14H2) Mouse mAb (upper) or Stat5 Antibody (lower).

Phospho-Stat5 (Tyr694) (C11C5) Rabbit mAb - 9359 from Cell Signaling Technology

Prices $297.00, $699.00
Sizes 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Monoclonal
Clone C11C5
Western blot analysis of extracts from K562 cells, untreated or treated with Gleevec, using Phospho-Stat5 (Tyr694) (C11C5) Rabbit mAb.

Stat5 Antibody - 9363 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using the Stat5 Antibody.

Stat5a (4H1) Mouse mAb - 4807 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 4H1
Western blot analyis of extracts from K-562, MOLT-4 and TF-1 cells using Stat5a (4H1) Mouse mAb.

Stat5 (3H7) Rabbit mAb - 9358 from Cell Signaling Technology

Host Rabbit
Clonality Monoclonal
Clone 3H7
Western blot analysis of extracts from HeLa, L929 and PC12 cells, using Stat5 (3H7) Rabbit mAb.

Phospho-Stat5 (Tyr694) (73E3) Rabbit mAb - 9354 from Cell Signaling Technology

Host Rabbit
Clonality Monoclonal
Clone 73E3
Western blot analysis of extracts from HeLa and Jurkat cells treated with or without IFN-α for 15 minutes, using Phospho-Stat5 Rabbit mAb, #9354 (upper), or total Stat5 Antibody, #9310 (lower).

Stat5 Antibody - 9352 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Stat5 Antibody - 9310 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Rex-1 (E-11) - sc-377095 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rex-1 (E-11): sc-377095. Western blot analysis of Rex-1 expression in PC-3 (A) and DU 145 (B) nuclear extracts.

Stat5 (A-9) - sc-74442 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat5 (A-9): sc-74442. Western blot analysis of Stat5 expression in K-562 (A) whole cell lysate and K-562 nuclear extract (B).

Stat5 (C-17) - sc-835 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat5 (C-17): sc-835. Immunofluorescence staining of methanol-fixed K-562 cells showing nuclear staining.

Stat5 (H-134) - sc-28685 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat5 (H-134): sc-28685. Immunofluorescence staining of methanol-fixed K-562 cells showing nuclear localization.

Stat5 (N-20) - sc-836 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat5 (N-20): sc-836. Immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse lymph node tissue showing cytoplasmic localization.

Stat5a (A-7) - sc-166479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat5a (A-7): sc-166479. Western blot analysis of Stat5a expression in I-11.15 (A) and L8 (B) whole cell lysates.

Stat5a (C-6) - sc-271542 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat5a (C-6): sc-271542. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tissue showing nuclear and cytoplasmic staining of glandular cells.

Stat5a (C-10) - sc-166465 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat5a (C-10): sc-166465. Western blot analysis of Stat5a expression in K-562 whole cell lysate.
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