| Gene Symbol |
STAT5A
|
| Entrez Gene |
6776
|
| Alt Symbol |
MGF, STAT5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal transducer and activator of transcription 5A
|
| Other Description |
-
|
| Swissprots |
Q1KLZ6 P42229
|
| Accessions |
CAD19637 CAG32953 CBX53841 EAW60819 P42229 AB208972 BAD92209 AK291650 BAF84339 AK301457 BAH13486 AK310632 AK310713 BC027036 AAH27036 DQ471288 ABF17939 DQ891723 ABM82649 DQ894900 ABM85826 L41142 AAA73962 U43185 AAB06589 XM_005257624 XP_005257681 NM_001288718 NP_001275647 NM_001288719 NP_001275648 NM_001288720 NP_001275649 NM_003152 NP_003143
|
| Function |
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. {ECO:0000269|PubMed:11773439, ECO:0000269|PubMed:15534001}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15534001}. Nucleus {ECO:0000269|PubMed:15534001}. Note=Translocated into the nucleus in response to phosphorylation.
|
| Top Pathways |
HTLV-I infection, Prolactin signaling pathway, Viral carcinogenesis, Measles, Jak-STAT signaling pathway
|