Gene Symbol | STAT5A |
---|---|
Entrez Gene | 6776 |
Alt Symbol | MGF, STAT5 |
Species | Human |
Gene Type | protein-coding |
Description | signal transducer and activator of transcription 5A |
Other Description | - |
Swissprots | Q1KLZ6 P42229 |
Accessions | CAD19637 CAG32953 CBX53841 EAW60819 P42229 AB208972 BAD92209 AK291650 BAF84339 AK301457 BAH13486 AK310632 AK310713 BC027036 AAH27036 DQ471288 ABF17939 DQ891723 ABM82649 DQ894900 ABM85826 L41142 AAA73962 U43185 AAB06589 XM_005257624 XP_005257681 NM_001288718 NP_001275647 NM_001288719 NP_001275648 NM_001288720 NP_001275649 NM_003152 NP_003143 |
Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. {ECO:0000269|PubMed:11773439, ECO:0000269|PubMed:15534001}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15534001}. Nucleus {ECO:0000269|PubMed:15534001}. Note=Translocated into the nucleus in response to phosphorylation. |
Top Pathways | HTLV-I infection, Prolactin signaling pathway, Viral carcinogenesis, Measles, Jak-STAT signaling pathway |
SignalSilence ® Stat5 siRNA I - 6275 from Cell Signaling Technology
|
||||||||
SignalSilence ® Stat5 siRNA II - 6298 from Cell Signaling Technology
|
||||||||
Stat5a CRISPR/Cas9 KO Plasmid (h) - sc-400150 from Santa Cruz Biotechnology
|
||||||||
Stat5a HDR Plasmid (h) - sc-400150-HDR from Santa Cruz Biotechnology
|
||||||||
Stat5a Double Nickase Plasmid (h) - sc-400150-NIC from Santa Cruz Biotechnology
|
||||||||
Stat5a Double Nickase Plasmid (h2) - sc-400150-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Stat5a CRISPR Activation Plasmid (h) - sc-400150-ACT from Santa Cruz Biotechnology
|
||||||||
Stat5a CRISPR Activation Plasmid (h2) - sc-400150-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Stat5a Lentiviral Activation Particles (h) - sc-400150-LAC from Santa Cruz Biotechnology
|
||||||||
Stat5a Lentiviral Activation Particles (h2) - sc-400150-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Stat5 siRNA (h) - sc-29495 from Santa Cruz Biotechnology
|
||||||||
Stat5 shRNA Plasmid (h) - sc-29495-SH from Santa Cruz Biotechnology
|
||||||||
Stat5 shRNA (h) Lentiviral Particles - sc-29495-V from Santa Cruz Biotechnology
|
||||||||
Stat5a siRNA (h) - sc-37008 from Santa Cruz Biotechnology
|
||||||||
Stat5a shRNA Plasmid (h) - sc-37008-SH from Santa Cruz Biotechnology
|
||||||||
Stat5a shRNA (h) Lentiviral Particles - sc-37008-V from Santa Cruz Biotechnology
|
||||||||
STAT5a RNAi - H00006776-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU108151 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20711 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20711 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR08738 from Sigma-Aldrich
|
||||||||
STAT5A siRNA (Human) - CRH4633 from Cohesion Biosciences
|
||||||||
STAT5A - MBS8216770 from MyBioSource
|
||||||||
STAT5A shRNA Plasmid (Human) - CHH4633 from Cohesion Biosciences
|