STAT5A

Gene Symbol STAT5A
Entrez Gene 6776
Alt Symbol MGF, STAT5
Species Human
Gene Type protein-coding
Description signal transducer and activator of transcription 5A
Other Description -
Swissprots Q1KLZ6 P42229
Accessions CAD19637 CAG32953 CBX53841 EAW60819 P42229 AB208972 BAD92209 AK291650 BAF84339 AK301457 BAH13486 AK310632 AK310713 BC027036 AAH27036 DQ471288 ABF17939 DQ891723 ABM82649 DQ894900 ABM85826 L41142 AAA73962 U43185 AAB06589 XM_005257624 XP_005257681 NM_001288718 NP_001275647 NM_001288719 NP_001275648 NM_001288720 NP_001275649 NM_003152 NP_003143
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. {ECO:0000269|PubMed:11773439, ECO:0000269|PubMed:15534001}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15534001}. Nucleus {ECO:0000269|PubMed:15534001}. Note=Translocated into the nucleus in response to phosphorylation.
Top Pathways HTLV-I infection, Prolactin signaling pathway, Viral carcinogenesis, Measles, Jak-STAT signaling pathway

SignalSilence ® Stat5 siRNA I - 6275 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® Stat5 siRNA I (+), or SignalSilence ® Stat5 siRNA II #6298 (+), using Stat5 (3H7) Rabbit mAb #9358 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The Stat5 (3H7) Rabbit mAb confirms silencing of Stat5 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

SignalSilence ® Stat5 siRNA II - 6298 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® Stat5 siRNA I #6275 (+), or SignalSilence ® Stat5 siRNA II (+), using Stat5 (3H7) Rabbit mAb #9358 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The Stat5 (3H7) Rabbit mAb confirms silencing of Stat5 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

Stat5a CRISPR/Cas9 KO Plasmid (h) - sc-400150 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a HDR Plasmid (h) - sc-400150-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a Double Nickase Plasmid (h) - sc-400150-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a Double Nickase Plasmid (h2) - sc-400150-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a CRISPR Activation Plasmid (h) - sc-400150-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a CRISPR Activation Plasmid (h2) - sc-400150-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a Lentiviral Activation Particles (h) - sc-400150-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5a Lentiviral Activation Particles (h2) - sc-400150-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Stat5 siRNA (h) - sc-29495 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Stat5 shRNA Plasmid (h) - sc-29495-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Stat5 shRNA (h) Lentiviral Particles - sc-29495-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Stat5a siRNA (h) - sc-37008 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Stat5a shRNA Plasmid (h) - sc-37008-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Stat5a shRNA (h) Lentiviral Particles - sc-37008-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAT5a RNAi - H00006776-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU108151 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20711 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20711 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08738 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08738

STAT5A siRNA (Human) - CRH4633 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STAT5A - MBS8216770 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STAT5A shRNA Plasmid (Human) - CHH4633 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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