| Gene Symbol |
BSN
|
| Entrez Gene |
8927
|
| Alt Symbol |
ZNF231
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
bassoon presynaptic cytomatrix protein
|
| Other Description |
bassoon (presynaptic cytomatrix protein)|neuronal double zinc finger protein|protein bassoon|zinc finger protein 231
|
| Swissprots |
Q9UPA5 O43161 Q7LGH3
|
| Accessions |
CAA77176 EAW64992 EAW64993 Q9UPA5 AB007894 BAA23707 AF052224 AAC83555 AW131629 NM_003458 NP_003449
|
| Function |
Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. {ECO:0000250}.
|
| Tissue Specificity |
Exclusively expressed in brain. {ECO:0000269|PubMed:9806829}.
|