Gene Symbol | BSN |
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Entrez Gene | 8927 |
Alt Symbol | ZNF231 |
Species | Human |
Gene Type | protein-coding |
Description | bassoon presynaptic cytomatrix protein |
Other Description | bassoon (presynaptic cytomatrix protein)|neuronal double zinc finger protein|protein bassoon|zinc finger protein 231 |
Swissprots | Q9UPA5 O43161 Q7LGH3 |
Accessions | CAA77176 EAW64992 EAW64993 Q9UPA5 AB007894 BAA23707 AF052224 AAC83555 AW131629 NM_003458 NP_003449 |
Function | Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. {ECO:0000250}. |
Tissue Specificity | Exclusively expressed in brain. {ECO:0000269|PubMed:9806829}. |
bassoon CRISPR/Cas9 KO Plasmid (h) - sc-406918 from Santa Cruz Biotechnology
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bassoon HDR Plasmid (h) - sc-406918-HDR from Santa Cruz Biotechnology
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bassoon Double Nickase Plasmid (h) - sc-406918-NIC from Santa Cruz Biotechnology
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bassoon Double Nickase Plasmid (h2) - sc-406918-NIC-2 from Santa Cruz Biotechnology
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bassoon CRISPR Activation Plasmid (h) - sc-406918-ACT from Santa Cruz Biotechnology
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bassoon CRISPR Activation Plasmid (h2) - sc-406918-ACT-2 from Santa Cruz Biotechnology
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bassoon Lentiviral Activation Particles (h) - sc-406918-LAC from Santa Cruz Biotechnology
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bassoon Lentiviral Activation Particles (h2) - sc-406918-LAC-2 from Santa Cruz Biotechnology
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bassoon siRNA (h) - sc-42168 from Santa Cruz Biotechnology
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bassoon shRNA Plasmid (h) - sc-42168-SH from Santa Cruz Biotechnology
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bassoon shRNA (h) Lentiviral Particles - sc-42168-V from Santa Cruz Biotechnology
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Bassoon RNAi - H00008927-R01 from Novus Biologicals
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MISSION® esiRNA - EHU021781 from Sigma-Aldrich
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MISSION® esiRNA - EHU010961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4078 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4078 from Sigma-Aldrich
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BSN siRNA (Human) - CRH5902 from Cohesion Biosciences
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BSN - MBS8234785 from MyBioSource
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shRNA set against Human BSN (NM_003458.3) - SHH247966 from Creative biogene
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shRNA set against Human BSN(NM_003458.3) - SHG106179 from Creative biogene
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bassoon CRISPR/Cas9 KO Plasmid (h2) - sc-406918-KO-2 from Santa Cruz Biotechnology
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bassoon HDR Plasmid (h2) - sc-406918-HDR-2 from Santa Cruz Biotechnology
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BSN shRNA Plasmid (Human) - CHH5902 from Cohesion Biosciences
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BSN miRNA 3'UTR clone - MiUTR1H-00956 from Creative biogene
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