Gene Symbol | C1GALT1 |
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Entrez Gene | 56913 |
Alt Symbol | C1GALT, T-synthase |
Species | Human |
Gene Type | protein-coding |
Description | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
Other Description | B3Gal-T8|core 1 O-glycan T-synthase|core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1|core 1 beta3-Gal-T1|core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
Swissprots | Q9BTU1 Q96QH4 Q9NS00 |
Accessions | AAQ96887 CAC43870 CCF77051 EAL24308 EAW93588 EAW93589 EAW93590 Q9NS00 AA443459 AF155582 AAF81981 AI400132 AI471988 AJ132443 CAC45046 AJ243256 CAC80435 AJ278960 CAC82373 AK023557 AK309328 BC003174 AAH03174 CB992707 CN360565 DA977378 DB106731 DB136152 XM_005249812 XP_005249869 XM_011515453 XP_011513755 XM_011515454 XP_011513756 XM_011515455 XP_011513757 XM_011515456 XP_011513758 NM_020156 NP_064541 |
Function | Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. Highly expressed in kidney, heart, placenta and liver. {ECO:0000269|PubMed:11677243}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Blood Group N antigen (DRF-8) - sc-52374 from Santa Cruz Biotechnology
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C1GALT1 (F-31) - sc-100745 from Santa Cruz Biotechnology
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C1GALT1 (H-300) - sc-98433 from Santa Cruz Biotechnology
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Anti-C1GALT1 antibody - ab57492 from Abcam
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Anti-C1GALT1 antibody - ab180250 from Abcam
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Anti-C1GALT1 Antibody (aa251-300) - LS-C107725 from LifeSpan Bioscience
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Anti-C1GALT1 Antibody (clone 1F1) - LS-C105161 from LifeSpan Bioscience
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Anti-C1GALT1 Antibody (aa115-144) - LS-C203991 from LifeSpan Bioscience
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C1GALT1 Antibody (1F1) - H00056913-M01 from Novus Biologicals
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C1GALT1 Antibody - NBP1-88477 from Novus Biologicals
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C1GALT1 Antibody - NBP1-88476 from Novus Biologicals
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C1GALT1 Antibody - NBP1-69602 from Novus Biologicals
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C1GALT1 Antibody - H00056913-A01 from Novus Biologicals
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C1GALT1 Polyclonal Antibody - bs-9685R from Bioss
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Monoclonal Anti-C1GALT1 antibody produced in mouse - WH0056913M1 from Sigma-Aldrich
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Anti-C1GALT1 antibody produced in rabbit - HPA011294 from Sigma-Aldrich
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Anti-C1GALT1 antibody produced in rabbit - HPA012819 from Sigma-Aldrich
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C1GALT1 antibody - middle region (ARP49478_P050) - ARP49478_P050 from Aviva Systems Biology
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C1GALT1-Antibody-monoclonal-M01 - AT1334a from Abgent, a WuXi AppTec company
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C1GALT1-Antibody-Center - AP20432c from Abgent, a WuXi AppTec company
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C1GALT1-Antibody-Center - AW5281 from Abgent, a WuXi AppTec company
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C1GALT1 antibody, Internal - GTX46062 from GeneTex
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C1GALT1 Antibody - middle region (OAAB17958) - OAAB17958 from Aviva Systems Biology
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C1GALT1 antibody - 70R-7429 from Fitzgerald
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C1GALT1 Antibody - abx034801 from Abbexa
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