SIL1

Gene Symbol SIL1
Entrez Gene 64374
Alt Symbol BAP, MSS, ULG5
Species Human
Gene Type protein-coding
Description SIL1 nucleotide exchange factor
Other Description BiP-associated protein|SIL1 homolog, endoplasmic reticulum chaperone|nucleotide exchange factor SIL1
Swissprots Q8N2L3 D3DQC2 Q9H173
Accessions CAF86460 EAW62120 EAW62121 Q9H173 AF547994 AAN84477 AJ299442 CAC17773 AK074624 BAC11096 AK075177 BAC11452 AY358950 AAQ89309 BC011568 AAH11568 BI561751 CA415266 CB125000 CD369479 DQ059315 AAY89591 DQ173771 ABA60425 DQ173772 ABA60426 EU176328 ABW03779 EU176671 ABW03472 XM_011543570 XP_011541872 NM_001037633 NP_001032722 NM_022464 NP_071909
Function Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5. {ECO:0000269|PubMed:12356756}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:12356756, ECO:0000269|PubMed:16282978}.
Tissue Specificity Highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. Also expressed in colon, heart, lung, ovary, pancreas, peripheral leukocyte, prostate, spleen and thymus. Expressed at low levels throughout the brain. {ECO:0000269|PubMed:12356756, ECO:0000269|PubMed:16282978}.
Top Pathways Protein processing in endoplasmic reticulum

SIL1 (Q-18) - sc-49737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SIL1 antibody - ab5639 from Abcam

Prices $380.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SIL1 antibody - ab175981 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SIL1 antibody (ab175981) at 1/1000 dilution + Mouse kidney tissue lysates at 35 µg

Anti-SIL1 antibody - ab115554 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SIL1 antibody (ab115554) at 1 µg/ml + Human Kidney lysate (RIPA buffer) at 30 µgdeveloped using the ECL technique

Anti-SIL1 antibody - ab89678 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-SIL1 antibody (ab89678) at 1 µg/ml + HeLa cell lysate at 50 µg

Anti-SIL1 antibody - ab82644 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SIL1 antibody (ab82644) at 1 µg/ml + HeLa cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SIL1 antibody [1C4] - ab118155 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C4
All lanes : Anti-SIL1 antibody [1C4] (ab118155) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY SIL1 cDNALysates/proteins at 5 µg per lane.

Anti-SIL1 antibody - C-terminal - ab155121 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SIL1 antibody - C-terminal (ab155121) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-BAP / SIL1 Antibody (clone 3E3) - LS-C115047 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E3
IHC of paraffin-embedded liver tissue using anti-SIL1 mouse monoclonal antibody. (Dilution 1:50).

Anti-BAP / SIL1 Antibody (clone 1C4) - LS-C115086 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C4
IHC of paraffin-embedded Carcinoma of prostate tissue using anti-SIL1 mouse monoclonal antibody. (Dilution 1:50).

Anti-BAP / SIL1 Antibody (aa448-461) IHC-plus™ - LS-B3286 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SIL1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3286 concentration 5 ug/ml.

Anti-BAP / SIL1 Antibody (aa360-409) IHC-plus™ - LS-B11474 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BAP / SIL1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-BAP / SIL1 Antibody (Internal, AP) - LS-C245867 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (Internal, APC) - LS-C245868 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (Internal, Azide-free, HRP) - LS-C247869 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (Internal, FITC) - LS-C245870 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (Internal, PE) - LS-C245871 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (Internal, Biotin) - LS-C245869 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (Internal) - LS-C328671 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAP / SIL1 Antibody (aa54-103) - LS-C80679 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SIL1 antibody LS-C80679 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

Anti-BAP / SIL1 Antibody (aa99-126) - LS-C161096 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SIL1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-BAP / SIL1 Antibody (clone 1G7) - LS-C115046 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G7
IHC of paraffin-embedded liver tissue using anti-SIL1 mouse monoclonal antibody. (Dilution 1:50).

SIL1 Antibody (3E3) - NBP2-02377 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E3
Western Blot: SIL1 Antibody (3E3) [NBP2-02377] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIL1.

SIL1 Antibody - NBP2-20365 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIL1 Antibody - NBP2-20364 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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