Gene Symbol | CASP14 |
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Entrez Gene | 23581 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | caspase 14, apoptosis-related cysteine peptidase |
Other Description | CASP-14|apoptosis-related cysteine protease|caspase 14, apoptosis-related cysteine protease|caspase-14 |
Swissprots | O95823 Q3SYC9 P31944 |
Accessions | EAW84459 P31944 AF097874 AAD16173 AK313992 BAG36704 BC069541 AAH69541 BC103868 AAI03869 BC103869 AAI03870 BM840054 EU262664 ABX83060 EU502748 ACA63845 HQ448424 ADQ32904 XM_011527861 XP_011526163 NM_012114 NP_036246 |
Function | Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Nucleus. |
Tissue Specificity | Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels. {ECO:0000269|PubMed:11175259}. |
Caspase-14 peptide - ab72738 from Abcam
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Human Caspase-14 full length protein - ab173054 from Abcam
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Human Caspase-14 protein fragment - ab153240 from Abcam
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Recombinant Human Caspase-14 Protein - H00023581-Q01 from Novus Biologicals
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CASP14-Antibody-C-term-Blocking-Peptide - BP6846b from Abgent, a WuXi AppTec company
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Caspase-13 Inhibitor Z-LEED-FMK - FMK010 from R&D Systems
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Human CASP14 His tag protein - orb84102 from Biorbyt
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Human Caspase-14 protein - orb163536 from Biorbyt
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Human CASP14 protein - orb244072 from Biorbyt
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Caspase-14 - H00023581-Q01-10 from Acris Antibodies
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Caspase-14 - H00023581-Q01-25 from Acris Antibodies
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CASP14, Human, Recombinant - 19-CG19 from ARP American Research Products
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Recombinant Human CASP14 Enzyme - BP002641-CG19 from Syd Labs
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Recombinant Human CASP14, His tagged - CASP14-1168H from Creative Biomart
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CASP14 - PN201421 from Elabscience
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Recombinant Caspase 14 (CASP14) - RPA457Hu01 from Uscn Life Science Inc.
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Recombinant Caspase 14 (CASP14) - RPA457Mu01 from Uscn Life Science Inc.
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Recombinant Caspase 14 (CASP14) - RPA457Mu02 from Uscn Life Science Inc.
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Recombinant Caspase 14 (CASP14) - RPA457Ra01 from Uscn Life Science Inc.
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Human Caspase-14 / CASP14 Protein (His Tag) - 11856-H07E-20 from Sino Biological
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Caspase 14 p10 Blocking Peptide - CBP2584 from Cohesion Biosciences
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Caspase 14 p10 Peptide - BS5643P from Bioworld Technology
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Recombinant human Caspase-14 protein - CSB-EP004546HU CSB-BP004546HU CSB-MP004546HU from Cusabio
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Recombinant human Caspase-14 protein - CSB-YP004546HU from Cusabio
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Recombinant Human Caspase-14(CASP14) - CSB-YP004546HU CSB-EP004546HU CSB-BP004546HU CSB-MP004546HU from Cusabio
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