CASP14

Gene Symbol CASP14
Entrez Gene 23581
Alt Symbol -
Species Human
Gene Type protein-coding
Description caspase 14, apoptosis-related cysteine peptidase
Other Description CASP-14|apoptosis-related cysteine protease|caspase 14, apoptosis-related cysteine protease|caspase-14
Swissprots O95823 Q3SYC9 P31944
Accessions EAW84459 P31944 AF097874 AAD16173 AK313992 BAG36704 BC069541 AAH69541 BC103868 AAI03869 BC103869 AAI03870 BM840054 EU262664 ABX83060 EU502748 ACA63845 HQ448424 ADQ32904 XM_011527861 XP_011526163 NM_012114 NP_036246
Function Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels. {ECO:0000269|PubMed:11175259}.

caspase-14 CRISPR/Cas9 KO Plasmid (h) - sc-402687 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 HDR Plasmid (h) - sc-402687-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 Double Nickase Plasmid (h) - sc-402687-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 Double Nickase Plasmid (h2) - sc-402687-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 CRISPR Activation Plasmid (h) - sc-402687-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 CRISPR Activation Plasmid (h2) - sc-402687-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 Lentiviral Activation Particles (h) - sc-402687-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 Lentiviral Activation Particles (h2) - sc-402687-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 siRNA (h) - sc-37364 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

caspase-14 shRNA Plasmid (h) - sc-37364-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

caspase-14 shRNA (h) Lentiviral Particles - sc-37364-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Caspase-14 RNAi - H00023581-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU056041 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5383 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5383 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CASP14 siRNA (Human) - CRH8372 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CASP14 - MBS8233293 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

caspase-14 CRISPR/Cas9 KO Plasmid (h2) - sc-402687-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-14 HDR Plasmid (h2) - sc-402687-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human CASP14 (NM_012114.2) - SHH254949 from Creative biogene

Category siRNA
Species Reactivities Human

Human CASP14 siRNA - orb268874 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CASP14 shRNA Plasmid (Human) - CHH8372 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CASP14 miRNA 3'UTR clone - MiUTR4H-TG01641 from Creative biogene

Species Reactivities Human
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