| Gene Symbol |
UBQLN4
|
| Entrez Gene |
56893
|
| Alt Symbol |
A1U, A1Up, C1orf6, CIP75, UBIN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquilin 4
|
| Other Description |
ataxin-1 interacting ubiquitin-like protein|ataxin-1 ubiquitin-like interacting protein|ataxin-1 ubiquitin-like-interacting protein A1U|connexin43-interacting protein of 75 kDa|ubiquilin-4
|
| Swissprots |
Q5VYA0 Q9BR98 Q9NRR5 Q5VYA1 A6ND44 B2RAY7 Q9UHX4
|
| Accessions |
EAW53005 EAW53006 EAW53007 EAW53008 EAW53009 Q9NRR5 AB209566 BAD92803 AF113544 AAF19084 AF188240 AAF80171 AI074831 AK098368 AK302895 BAG64068 AK314413 BAG37034 BC006410 AAH06410 BC018403 AAH18403 BC063841 AAH63841 DC334851 HY061664 XM_005245347 XP_005245404 XM_005245348 XP_005245405 XR_921895 NM_001304342 NP_001291271 NM_020131 NP_064516
|
| Function |
Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation. {ECO:0000269|PubMed:15280365}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Endoplasmic reticulum {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Colocalizes with the proteasome, both in nucleus and cytoplasm. May associate with the endoplasmic reticulum.
|
| Tissue Specificity |
Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. {ECO:0000269|PubMed:11001934}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|