UBQLN4

Gene Symbol UBQLN4
Entrez Gene 56893
Alt Symbol A1U, A1Up, C1orf6, CIP75, UBIN
Species Human
Gene Type protein-coding
Description ubiquilin 4
Other Description ataxin-1 interacting ubiquitin-like protein|ataxin-1 ubiquitin-like interacting protein|ataxin-1 ubiquitin-like-interacting protein A1U|connexin43-interacting protein of 75 kDa|ubiquilin-4
Swissprots Q5VYA0 Q9BR98 Q9NRR5 Q5VYA1 A6ND44 B2RAY7 Q9UHX4
Accessions EAW53005 EAW53006 EAW53007 EAW53008 EAW53009 Q9NRR5 AB209566 BAD92803 AF113544 AAF19084 AF188240 AAF80171 AI074831 AK098368 AK302895 BAG64068 AK314413 BAG37034 BC006410 AAH06410 BC018403 AAH18403 BC063841 AAH63841 DC334851 HY061664 XM_005245347 XP_005245404 XM_005245348 XP_005245405 XR_921895 NM_001304342 NP_001291271 NM_020131 NP_064516
Function Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation. {ECO:0000269|PubMed:15280365}.
Subcellular Location Nucleus. Cytoplasm. Endoplasmic reticulum {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Colocalizes with the proteasome, both in nucleus and cytoplasm. May associate with the endoplasmic reticulum.
Tissue Specificity Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. {ECO:0000269|PubMed:11001934}.
Top Pathways Protein processing in endoplasmic reticulum

A1Up (T-12) - sc-136560 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
A1Up (T-12): sc-136560. Western blot analysis of A1Up expression in HeLa (A), K-562 (B), IMR-32 (C) and SH-SY-5Y (D) nuclear extracts.

A1Up (P-12) - sc-136559 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
A1Up (P-12): sc-136559. Western blot analysis of A1Up expression in non-transfected: sc-117752 (A) and human A1Up transfected: sc-117281 (B) 293T whole cell lysates.

A1Up (N-12) - sc-136558 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
A1Up (N-12): sc-136558. Western blot analysis of A1Up expression in non-transfected: sc-117752 (A) and human A1Up transfected: sc-117281 (B) 293T whole cell lysates.

A1Up (M398) - sc-136146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
A1Up (M398): sc-136146. Western blot analysis of A1Up expression in non-transfected 293T: sc-117752 (A), human A1Up transfected 293T: sc-117281 (B), K-562 (C), TE671 (D) and IMR-32 (E) whole cell lysates.

A1Up (L64) - sc-136144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
A1Up (L64): sc-136144. Western blot analysis of A1Up expression in non-transfected 293T: sc-117752 (A), human A1Up transfected 293T: sc-117281 (B), K-562 (C), TE671 (D) and IMR-32 (E) whole cell lysates.

A1Up (A333) - sc-136145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
A1Up (A333): sc-136145. Western blot analysis of A1Up expression in non-transfected 293T: sc-117752 (A), human A1Up transfected 293T: sc-117281 (B), HeLa (C), K-562 (D), TE671 (E) and IMR-32 (F) whole cell lysates.

Anti-UBQLN4 antibody - ab106443 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-UBQLN4 antibody (ab106443) at 1 µg/mlLane 2 : Anti-UBQLN4 antibody (ab106443) at 2 µg/mlLane 1 : 3T3 cell lysateLane 2 : 3T3 cell lysateLysates/proteins at 15 µg per lane.

Anti-UBQLN4 antibody - ab92674 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-UBQLN4 antibody (ab92674) at 1/500 dilutionLane 1 : Mouse brain lysate without blocking peptide Lane 2 : Mouse brain lysate with blocking peptide at 10µgLysates/proteins at 30 µg per lane.

Anti-UBQLN4 antibody - ab154728 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-UBQLN4 antibody (ab154728) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : HeLa whole cell lysateLane 4 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-UBQLN4 Antibody (N-Terminus) - LS-C108556 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of CIP75 in 3T3 cell lysate with CIP75 antibody at (A) 1 and (B) 2 ug/ml. Below: Immunohistochemistry of CIP75 in mouse kidney tissue with CIP75 antibody at 5 ug/ml.

Anti-UBQLN4 Antibody (aa287-336) - LS-C112040 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UBQLN4 antibody LS-C112040 Western blot of HT1080 cell lysate.

Anti-UBQLN4 Antibody (aa451-500) - LS-C201695 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human ACHN. UBQLN4 antibody dilution 1.0 ug/ml.

Anti-UBQLN4 Antibody (aa201-250) - LS-C120441 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma tissue, using UBQLN4 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-UBQLN4 Antibody (aa1-30) - LS-C203899 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Ubiquilin 4 Antibody western blot of 293 cell line lysates (35 ug/lane). The Ubiquilin 4 antibody detected the Ubiquilin 4 protein (arrow).

UBQLN4/CIP75 Antibody - NBP2-20793 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBQLN4/CIP75 Antibody [NBP2-20793] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 7. 5% SDS PAGE gel, diluted at 1:1000.

UBQLN4/CIP75 Antibody - NBP1-56383 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBQLN4/CIP75 Antibody [NBP1-56383] - HT1080 cell lysate, concentration 0.2-1 ug/ml.

UBQLN4/CIP75 Antibody - NBP1-77054 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: UBQLN4/CIP75 Antibody [NBP1-77054] - 3T3 cell lysate with UBQLN4/CIP75 antibody at (A) 1 and (B) 2 ug/ml.

Anti-UBQLN4 antibody produced in rabbit - HPA027920 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBQLN4: <B>Cat. No. HPA027920</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells of seminiferus ducts.

ANTI-UBIQUILIN 4(N-TERMINAL) antibody produced in rabbit - SAB1306728 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Ubiquilin 4 (N-term): <B>Cat. No. SAB1306728</B>: Ubiquilin 4 Antibody (N-term) western blot analysis in 293 cell line lysates (35 μg/lane).

Anti-CIP75 antibody produced in rabbit - SAB3500075 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CIP75: <B>Cat. No. SAB3500075</B>: CIP75 in mouse kidney tissue with CIP75 antibody at 5 μg/mL.

Anti-UBQLN4 antibody produced in rabbit - SAB4502434 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBQLN4: <B>Cat. No. SAB4502434</B>: Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Anti-UBQLN4 antibody. Cells on the left were treated with the Anti-UBQLN4 antibody. Cells on the right (negative control) were treated with both Anti-UBQLN4 antibody and the synthesized immunogen peptide.

UBQLN4 antibody - middle region (ARP57355_P050) - ARP57355_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UBQLN4 Antibody - C-terminal region (ARP57356_P050) - ARP57356_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ubiquilin-4-Antibody-N-term - AP20424a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Ubiquilin 4 Antibody (N-term) (Cat. #AP20424a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Ubiquilin 4 antibody detected the Ubiquilin 4 protein (arrow).

CIP75 antibody - GTX85267 from GeneTex

Prices $329.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-CIP75 antibody used in Immunohistochemistry. GTX85267
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