Gene Symbol | LAGE3 |
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Entrez Gene | 8270 |
Alt Symbol | CVG5, DXS9879E, DXS9951E, ESO3, ITBA2 |
Species | Human |
Gene Type | protein-coding |
Description | L antigen family, member 3 |
Other Description | EKC/KEOPS complex subunit LAGE3|protein ESO-3 |
Swissprots | Q5HY39 Q8IZ78 Q14657 |
Accessions | EAW72701 Q14657 BC015744 AAH15744 BC019012 BC062330 AAH62330 BQ649305 EU832327 ACE87584 EU832412 ACE86897 HQ448067 ADQ32548 X92896 CAA63489 NM_006014 NP_006005 |
Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22912744}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384295, ECO:0000269|PubMed:8786131}. |
LAGE-3 (D-17) - sc-243230 from Santa Cruz Biotechnology
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LAGE-3 (T-20) - sc-243232 from Santa Cruz Biotechnology
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Anti-LAGE3 Antibody (N-Terminus) - LS-C201798 from LifeSpan Bioscience
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LAGE3 Antibody - NBP2-32715 from Novus Biologicals
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LAGE3 Antibody - NBP1-94092 from Novus Biologicals
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Anti-LAGE3 antibody produced in rabbit - HPA036122 from Sigma-Aldrich
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Anti-LAGE3 antibody produced in rabbit - HPA036123 from Sigma-Aldrich
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LAGE3 Antibody - N-terminal region (ARP70749_P050) - ARP70749_P050 from Aviva Systems Biology
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LAGE3 antibody - 18883-1-AP from Proteintech Group
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LAGE3, Polyclonal Antibody - MBS2523719 from MyBioSource
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LAGE3 Antibody - EPP14817 from Elabscience
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LAGE3-Antibody-N-terminal-region-AI15872 - AI15872 from Abgent, a WuXi AppTec company
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LAGE3 antibody - TA337406 from Acris Antibodies
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Anti-LAGE3 Antibody (N-Terminus, Biotin) - LS-C477787 from LifeSpan Bioscience
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Anti-LAGE3 Antibody (N-Terminus, FITC) - LS-C477788 from LifeSpan Bioscience
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Anti-LAGE3 Antibody (N-Terminus, HRP) - LS-C477789 from LifeSpan Bioscience
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Anti-LAGE3 polyclonal antibody - CABT-BL2112 from Creative Diagnostics
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Anti-LAGE3 Antibody A15245 - A15245 from Boster Bio
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LAGE3 Antibody - N-terminal region : Biotin (ARP70749_P050-Biotin) - ARP70749_P050-Biotin from Aviva Systems Biology
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LAGE3 Antibody - N-terminal region : FITC (ARP70749_P050-FITC) - ARP70749_P050-FITC from Aviva Systems Biology
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LAGE3 Antibody - N-terminal region : HRP (ARP70749_P050-HRP) - ARP70749_P050-HRP from Aviva Systems Biology
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LAGE3 antibody - center region (OAAB02369) - OAAB02369 from Aviva Systems Biology
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