LAGE3

Gene Symbol LAGE3
Entrez Gene 8270
Alt Symbol CVG5, DXS9879E, DXS9951E, ESO3, ITBA2
Species Human
Gene Type protein-coding
Description L antigen family, member 3
Other Description EKC/KEOPS complex subunit LAGE3|protein ESO-3
Swissprots Q5HY39 Q8IZ78 Q14657
Accessions EAW72701 Q14657 BC015744 AAH15744 BC019012 BC062330 AAH62330 BQ649305 EU832327 ACE87584 EU832412 ACE86897 HQ448067 ADQ32548 X92896 CAA63489 NM_006014 NP_006005
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:22912744}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:12384295, ECO:0000269|PubMed:8786131}.

LAGE-3 CRISPR/Cas9 KO Plasmid (h) - sc-411132 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 HDR Plasmid (h) - sc-411132-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 Double Nickase Plasmid (h) - sc-411132-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 Double Nickase Plasmid (h2) - sc-411132-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 CRISPR Activation Plasmid (h) - sc-411132-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 CRISPR Activation Plasmid (h2) - sc-411132-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 Lentiviral Activation Particles (h) - sc-411132-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 Lentiviral Activation Particles (h2) - sc-411132-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAGE-3 siRNA (h) - sc-90924 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LAGE-3 shRNA Plasmid (h) - sc-90924-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LAGE-3 shRNA (h) Lentiviral Particles - sc-90924-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU116631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11522 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11522 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07671 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07671

LAGE3 siRNA (Human) - CRH5418 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LAGE3 (NM_006014.3) - SHH328159 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LAGE3(NM_006014.3) - SHH141077 from Creative biogene

Category siRNA
Species Reactivities Human

Human LAGE3 siRNA - orb265920 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LAGE3 shRNA Plasmid (Human) - CHH5418 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LAGE3 miRNA 3'UTR clone - MiUTR3H-02529 from Creative biogene

Species Reactivities Human
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