KRAS

Gene Symbol	KRAS
Entrez Gene	3845
Alt Symbol	C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Species	Human
Gene Type	protein-coding
Description	Kirsten rat sarcoma viral oncogene homolog
Other Description	GTPase KRas\|K-Ras 2\|K-ras p21 protein\|PR310 c-K-ras oncogene\|c-Ki-ras\|c-Kirsten-ras protein\|cellular c-Ki-ras2 proto-oncogene\|oncogene KRAS2\|transforming protein p21\|v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
Swissprots	A8K8Z5 Q96D10 P01116 P01118 B0LPF9
Accessions	AAA36148 AAA36149 AAA36554 AAB59444 AAB59445 AAD13953 AAF91482 ABP96992 ABP97009 ABP97013 ABP97015 ABS10683 ABS10684 ABY87538 ADQ00188 AFF18187 AGC09594 CAA25828 CAA26593 CBK51852 CBK51925 CBV35640 CDL93479 EAW96511 EAW96512 EAW96513 EAW96514 P01116 AA812162 AF493917 AAM12631 AI539465 AK292510 BAF85199 AW117295 BC010502 BC013572 AAH13572 BC029545 BG258021 BT007153 AAP35817 CD245555 DQ890649 ABM81575 DQ893829 ABM84755 M17087 AAA36555 M35504 AAA35689 M35505 AAA35690 M54968 AAB41942 XM_006719069 XP_006719132 XM_011520653 XP_011518955 NM_004985 NP_004976 NM_033360 NP_203524
Function	Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). {ECO:0000269\|PubMed:22711838, ECO:0000269\|PubMed:23698361, ECO:0000305}.
Subcellular Location	Cell membrane {ECO:0000269\|PubMed:22431598, ECO:0000269\|PubMed:23698361}; Lipid-anchor {ECO:0000305\|PubMed:23698361}; Cytoplasmic side {ECO:0000305\|PubMed:23698361}. Cytoplasm, cytosol {ECO:0000269\|PubMed:23698361}.
Top Pathways	Axon guidance, Tight junction, VEGF signaling pathway, Gap junction, Natural killer cell mediated cytotoxicity

Ras (D2C1) Rabbit mAb - 8955 from Cell Signaling Technology

Prices	$246.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Monoclonal
Clone	D2C1

Western blot analysis of extracts from various cell lines using Ras (D2C1) Rabbit mAb.

Ras (G12V Mutant Specific) (D2H12) Rabbit mAb - 14412 from Cell Signaling Technology

Prices	$261.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Monoclonal
Clone	D2H12

Western blot analysis of extracts from various cell lines using Ras (G12V Mutant Specific) (D2H12) Rabbit mAb (upper), Ras (D2C1) Rabbit mAb #8955 (middle), and β-Actin (D6A8) #8457 (lower).

Ras (G12D Mutant Specific) (D8H7) Rabbit mAb - 14429 from Cell Signaling Technology

Prices	$261.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Monoclonal
Clone	D8H7

Western blot analysis of extracts from various cell lines using Ras (G12D Mutant Specific) (D8H7) Rabbit mAb (upper), Ras (D2C1) Rabbit mAb #8955 (middle), and β-Actin (D6A8) #8457 (lower).

K-Ras (F234) - sc-30 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

K-Ras (F234): sc-30. Western blot analysis of K-Ras expression in KNRK whole cell lysate.

K-Ras-2A (C-17) - sc-522 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

K-Ras-2A (C-17): sc-522. Immunofluorescence staining of methanol-fixed Sol8 cells showing cytoplasmic localization.

K-Ras-2B (C-19) - sc-521 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

K-Ras-2B (C-19): sc-521. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.

Anti-KRAS antibody - ab55391 from Abcam

Prices	$398.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-KRAS antibody - ab84573 from Abcam

Prices	$378.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody - ab137739 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody (ab137739) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

Anti-KRAS antibody - ab102007 from Abcam

Prices	$378.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-KRAS antibody (ab102007) at 1/250 dilutionLane 1 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 2 : Brain (Human) Membrane Lysate - adult normal tissue (ab29456)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-KRAS antibody - ab180772 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody (ab180772) at 1/200 dilution + Human brain cell lysate

Anti-KRAS antibody - ab137737 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody (ab137737) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-KRAS antibody - ab125430 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody (ab125430) at 1 µg/ml + Rat lung lysate at 10 µg

Anti-KRAS antibody [4F6] - ab157255 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	4F6

All lanes : Anti-KRAS antibody [4F6] (ab157255) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY KRASLysates/proteins at 5 µg per lane.

Anti-KRAS antibody - C-terminal - ab172949 from Abcam

Prices	$384.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody - C-terminal (ab172949) at 1/100 dilution + NIH-3T3 cell line lysate at 35 µg

Anti-KRAS antibody - C-terminal - ab196630 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS antibody - C-terminal (ab196630) at 1/200 dilution + brain cell lysatedeveloped using the ECL technique

Anti-KRAS Antibody (aa158-185) - LS-C165606 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

KRAS2 Antibody western blot of WiDr cell line and mouse lung tissue lysates (35 ug/lane). The KRAS2 antibody detected the KRAS2 protein (arrow).

Anti-KRAS Antibody (aa61-110) - LS-C146279 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

KRAS antibody LS-C146279 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.

Anti-KRAS Antibody (Internal) - LS-C137132 from LifeSpan Bioscience

Prices	$255.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS Antibody (N-Terminus, clone EPR3255) - LS-C138028 from LifeSpan Bioscience

Prices	$480.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR3255

Western blot analysis on (A) 293T and (B) SH-SY5Y cell lysates using anti-Ras antibody.

Anti-KRAS Antibody (clone 5H6) - LS-C175566 from LifeSpan Bioscience

Prices	$350.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	5H6

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KRAS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KRAS.

Anti-KRAS Antibody (clone 4F6) - LS-C175569 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	4F6

Anti-KRAS Antibody (HRP) - LS-C211371 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS Antibody (FITC) - LS-C211374 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-KRAS Antibody (Biotin) - LS-C211375 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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