IPO13

Gene Symbol	IPO13
Entrez Gene	9670
Alt Symbol	IMP13, KAP13, LGL2, RANBP13
Species	Human
Gene Type	protein-coding
Description	importin 13
Other Description	Ran binding protein 13|importin-13|karyopherin 13|karyopherin-13|late gestation lung 2|ran-binding protein 13
Swissprots	Q96HS3 O94829 Q9H8N3 Q9UFR1 Q7LC04 Q5T4X3 D3DPY4
Accessions	EAX07072 EAX07073 O94829 AB018267 BAA34444 AF267987 AAF73471 AK023441 BAB14575 AK091565 BAG52382 AK290173 BAF82862 AL117501 CAB55966 BC002608 AAH02608 BC008194 AAH08194 BX116797 JF432433 ADZ15650 XM_011542461 XP_011540763 NM_014652 NP_055467
Function	Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the l
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Expressed in fetal brain, heart, intestine and kidney. {ECO:0000269|PubMed:10745026}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Importin 13 full length protein - ab132161 from Abcam Category Protein Source Wheat germ Species Human

Human Importin 13 peptide - ab45564 from Abcam Category Peptide Species Human

Human Importin 13 protein fragment - ab127306 from Abcam Category Protein Source E. coli Species Human

Recombinant Human Importin-13 Protein - H00009670-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IPO13-Antibody-C-term-Blocking-peptide - BP5898b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RanBP13 / Importin-13 - H00009670-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RanBP13 / Importin-13 - H00009670-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IPO13 fusion protein - Ag2317 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

IPO13 fusion protein - ag18836 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

IPO13 fusion protein - Ag21084 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

Recombinant Human IPO13, GST-tagged - IPO13-143H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Importin-13(IPO13) ,partial - CSB-YP011776HU CSB-EP011776HU CSB-BP011776HU CSB-MP011776HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RanBP13 / Importin-13 (full length, C-term DDK tag) - TP710254 from Acris Antibodies Category Protein Prices $399.00 Sizes 20 µg Source SF9 cells Species Human

IPO13 Peptide, Human - M34GP07702H from Creative Peptides Category Peptide Source Synthetic. Species Human

Importin-13 (IPO13), partial, Recombinant Protein - MBS1187893 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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