KRT74

Gene Symbol KRT74
Entrez Gene 121391
Alt Symbol ADWH, HTSS2, HYPT3, K6IRS4, KRT5C, KRT6IRS4
Species Human
Gene Type protein-coding
Description keratin 74, type II
Other Description CK-74|K5C|K74|cytokeratin-74|keratin 5c|keratin 6 irs4|keratin, type II cytoskeletal 74|keratin-5c|keratin-74|type II inner root sheath-specific keratin-K6irs4|type-II keratin Kb37
Swissprots B5MD61 Q7RTS7 Q86Y45
Accessions DAA00404 EAW96637 Q7RTS7 AF086480 AI092341 AJ508777 CAD48514 BC160050 AAI60050 XM_011537902 XP_011536204 NM_175053 NP_778223
Function Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). {ECO:0000305}.
Tissue Specificity Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS Huxley layer, but not in Henle layer or cuticle of the IRS. In the IRS Huxley layer, it is expressed in specialized Huxley cells, termed 'Fluegelzellen, along the area of differentiated Henle cells (at protein level). {ECO:0000269|PubMed:12648212, ECO:0000269|PubMed:16874310, ECO:0000269|PubMed:24714551}.

Keratin 74 CRISPR/Cas9 KO Plasmid (h) - sc-414169 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 HDR Plasmid (h) - sc-414169-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 Double Nickase Plasmid (h) - sc-414169-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 Double Nickase Plasmid (h2) - sc-414169-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 CRISPR Activation Plasmid (h) - sc-414169-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 CRISPR Activation Plasmid (h2) - sc-414169-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 Lentiviral Activation Particles (h) - sc-414169-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 Lentiviral Activation Particles (h2) - sc-414169-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Keratin 74 siRNA (h) - sc-95780 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Keratin 74 shRNA Plasmid (h) - sc-95780-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Keratin 74 shRNA (h) Lentiviral Particles - sc-95780-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU146401 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN11399 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11399 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KRT74 siRNA (Human) - CRJ4672 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KRT74 (NM_175053.3) - SHH327659 from Creative biogene

Category siRNA
Species Reactivities Human

Human KRT74 siRNA - orb275173 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KRT74 shRNA Plasmid (Human) - CHJ4672 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KRT74 miRNA 3'UTR clone - MiUTR1H-05466 from Creative biogene

Species Reactivities Human
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