Gene Symbol | KRT74 |
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Entrez Gene | 121391 |
Alt Symbol | ADWH, HTSS2, HYPT3, K6IRS4, KRT5C, KRT6IRS4 |
Species | Human |
Gene Type | protein-coding |
Description | keratin 74, type II |
Other Description | CK-74|K5C|K74|cytokeratin-74|keratin 5c|keratin 6 irs4|keratin, type II cytoskeletal 74|keratin-5c|keratin-74|type II inner root sheath-specific keratin-K6irs4|type-II keratin Kb37 |
Swissprots | B5MD61 Q7RTS7 Q86Y45 |
Accessions | DAA00404 EAW96637 Q7RTS7 AF086480 AI092341 AJ508777 CAD48514 BC160050 AAI60050 XM_011537902 XP_011536204 NM_175053 NP_778223 |
Function | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). {ECO:0000305}. |
Tissue Specificity | Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS Huxley layer, but not in Henle layer or cuticle of the IRS. In the IRS Huxley layer, it is expressed in specialized Huxley cells, termed 'Fluegelzellen, along the area of differentiated Henle cells (at protein level). {ECO:0000269|PubMed:12648212, ECO:0000269|PubMed:16874310, ECO:0000269|PubMed:24714551}. |
Keratin 74 (E-6) - sc-390340 from Santa Cruz Biotechnology
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Keratin 74 (P-12) - sc-168291 from Santa Cruz Biotechnology
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Keratin 74 (C-14) - sc-168288 from Santa Cruz Biotechnology
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Anti-KRT74 antibody - ab168301 from Abcam
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Anti-KRT74 antibody - C-terminal - ab192719 from Abcam
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Anti-KRT74 antibody - C-terminal - ab135440 from Abcam
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Anti-KRT74 / Keratin 74 Antibody - LS-C193785 from LifeSpan Bioscience
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Anti-KRT74 / Keratin 74 Antibody (C-Terminus) - LS-C152203 from LifeSpan Bioscience
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Anti-KRT74 / Keratin 74 Antibody (aa106-155) - LS-C152204 from LifeSpan Bioscience
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KRT74 Antibody - NBP2-14645 from Novus Biologicals
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KRT74 Antibody - H00121391-B01P-50ug from Novus Biologicals
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Anti-KRT74 antibody produced in rabbit - HPA048596 from Sigma-Aldrich
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ANTI-KRT74 antibody produced in mouse - SAB1411889 from Sigma-Aldrich
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KRT74 Antibody - C-terminal region (ARP66601_P050) - ARP66601_P050 from Aviva Systems Biology
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KRT74 Antibody - N-terminal region (ARP66602_P050) - ARP66602_P050 from Aviva Systems Biology
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Cytokeratin 74 antibody - BP5099 from Acris Antibodies
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Cytokeratin 74 antibody - H00121391-B01P from Acris Antibodies
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Anti-Keratin K74 (K6irs14) - 03-GP-K6IRS4 from ARP American Research Products
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Keratin K74, Polyclonal Antibody - MBS833261 from MyBioSource
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Anti-KRT74 (full length) polyclonal antibody - DPABH-07052 from Creative Diagnostics
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Anti-KRT74 (aa 475-524) polyclonal antibody - DPABH-26080 from Creative Diagnostics
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Anti-KRT74 monoclonal antibody - DCABH-200815 from Creative Diagnostics
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KRT74-Antibody-N-terminal-region-AI15366 - AI15366 from Abgent, a WuXi AppTec company
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Cytokeratin 74 antibody - TA331332 from Acris Antibodies
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Cytokeratin 74 antibody - TA331333 from Acris Antibodies
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