| Gene Symbol |
Bcat1
|
| Entrez Gene |
12035
|
| Alt Symbol |
BCATc, Eca39
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
branched chain aminotransferase 1, cytosolic
|
| Other Description |
BCAT(c)|branched-chain-amino-acid aminotransferase, cytosolic
|
| Swissprots |
Q7TMT2 P24288
|
| Accessions |
EDL10671 EDL10672 P24288 AK012821 AK013888 BAB29038 AK036309 BAC29379 AK138468 BAE23671 AK166971 BAE39154 AK167232 BAE39356 AK167368 BAE39464 AK168249 BAE40199 AW491045 BC053706 AAH53706 BY781109 U42443 AAB05673 X17502 CAA35543 XM_006536024 XP_006536087 XM_011241566 XP_011239868 NM_001024468 NP_001019639 NM_007532 NP_031558
|
| Function |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Expressed in brain and kidney. Overexpressed in MYC-induced brain tumors, lymphomas, as well as in a teratocarcinoma cell line.
|
| Top Pathways |
Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Valine, leucine and isoleucine degradation, Pantothenate and CoA biosynthesis
|
