| Gene Symbol | Bcat1 |
|---|---|
| Entrez Gene | 12035 |
| Alt Symbol | BCATc, Eca39 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | branched chain aminotransferase 1, cytosolic |
| Other Description | BCAT(c)|branched-chain-amino-acid aminotransferase, cytosolic |
| Swissprots | Q7TMT2 P24288 |
| Accessions | EDL10671 EDL10672 P24288 AK012821 AK013888 BAB29038 AK036309 BAC29379 AK138468 BAE23671 AK166971 BAE39154 AK167232 BAE39356 AK167368 BAE39464 AK168249 BAE40199 AW491045 BC053706 AAH53706 BY781109 U42443 AAB05673 X17502 CAA35543 XM_006536024 XP_006536087 XM_011241566 XP_011239868 NM_001024468 NP_001019639 NM_007532 NP_031558 |
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. |
| Subcellular Location | Cytoplasm. |
| Tissue Specificity | Expressed in brain and kidney. Overexpressed in MYC-induced brain tumors, lymphomas, as well as in a teratocarcinoma cell line. |
| Top Pathways | Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Valine, leucine and isoleucine degradation, Pantothenate and CoA biosynthesis |