CDIPT

Gene Symbol CDIPT
Entrez Gene 10423
Alt Symbol PIS, PIS1
Species Human
Gene Type protein-coding
Description CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Other Description PI synthase|PtdIns synthase|phosphatidylinositol synthase
Swissprots Q6FGU1 B4DUV0 O14735 H3BTV1 Q6ZN70
Accessions EAW79976 EAW79977 EAW79978 O14735 AF014807 AAB94860 AI696848 AK094468 BAG52872 AK097691 BAG53514 AK131227 BAG54756 AK131349 BAD18505 AK222676 BAD96396 AK290632 BAF83321 AK300805 BAG62462 AK310988 AK314544 AL050383 BC001444 AAH01444 BI490060 BT007301 AAP35965 BX333193 CR542016 CAG46813 XM_005255038 XP_005255095 NM_001286585 NP_001273514 NM_001286586 NP_001273515 NM_006319 NP_006310 NM_145752
Function Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. {ECO:0000269|PubMed:8110188}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane {ECO:0000269|PubMed:8110188}.
Tissue Specificity Detected in placenta (at protein level). Widely expressed. Higher expression in adult liver and skeletal muscle, slightly lower levels seen in pancreas, kidney, lung, placenta, brain, heart, leukocyte, colon, small intestine, ovary, testis, prostate, thymus and spleen. In fetus, expressed in kidney, liver, lung and brain. {ECO:0000269|PubMed:8110188}.
Top Pathways Inositol phosphate metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system

CDIPT-Over-expression-Lysate - LY11106a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CDIPT (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDIPT gene

CDIPT 293 Cell Lysate - 407815 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CDIPT Overexpression Lysate (Native) - NBL1-09036 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CDIPT Overexpression Lysate (Adult Normal) [NBL1-09036] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDIPT.

CDIPT Over-expression Lysate Product - GWB-17BEC8 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human CDIPT Knockdown Stable Cell Line - CSC-DC002856 from Creative biogene

Category Cell Line
Species Human
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