Gene Symbol | NDOR1 |
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Entrez Gene | 27158 |
Alt Symbol | NR1, bA350O14.9 |
Species | Human |
Gene Type | protein-coding |
Description | NADPH dependent diflavin oxidoreductase 1 |
Other Description | NADPH-dependent FMN and FAD-containing oxidoreductase|NADPH-dependent diflavin oxidoreductase 1 |
Swissprots | Q96BC6 D3YTH9 Q5VSG4 Q9UHB4 D3YTG6 Q86US9 |
Accessions | EAW88366 Q9UHB4 AF199509 AAF25205 AK026089 AK074403 AK225995 AK290026 BAF82715 AL133632 AY077845 AAL77754 BC015735 AAH15735 BC078668 BC093782 AAH93782 BC111943 AAI11944 BC143229 DA408370 DA858250 DQ892229 ABM83155 DQ895429 ABM86355 XM_011518545 XP_011516847 XM_011518546 XP_011516848 XM_011518547 XP_011516849 XM_011518548 XP_011516850 XR_929763 XR_929764 NM_001144026 NP_001137498 NM_001144027 NP_001137499 NM_001144028 NP_001137500 NM_014434 NP_055249 |
Function | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins (By similarity). Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. {ECO:0000255|HAMAP-Rule:MF_03178, ECO:0000269|PubMed:10625700, ECO:0000269|PubMed:20802492, ECO:0000269|PubMed:23596212}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000255|HAMAP-Rule:MF_03178, ECO:0000269|PubMed:10625700, ECO:0000269|PubMed:12871939}. Note=Concentrated in perinuclear structure. |
Tissue Specificity | Low expression in brain, heart, kidney, pancreas, prostate and skeletal muscle. Highest levels in the placenta. Expressed in cancer cell lines including promyelocytic leukemia, HeLaS3, chronic myelagenous leukemia, lymphoblastic leukemia, Burkitt's lymphoma, colorectal adenocarcinoma, lung carcinoma, and melanoma G-361. {ECO:0000269|PubMed:12871939}. |
NDOR1 (C-13) - sc-160573 from Santa Cruz Biotechnology
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NDOR1 (G-15) - sc-160574 from Santa Cruz Biotechnology
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NDOR1 (XX-9) - sc-100482 from Santa Cruz Biotechnology
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Anti-NDOR1 antibody - ab173225 from Abcam
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Anti-NDOR1 antibody - ab106525 from Abcam
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Anti-NDOR1 antibody - ab57110 from Abcam
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Anti-NDOR1 antibody - ab172465 from Abcam
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Anti-NDOR1 antibody [1E3] - ab139291 from Abcam
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Anti-NDOR1 Antibody (clone 1E3) - LS-C337889 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234, AP) - LS-C215933 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234, APC) - LS-C215934 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234, Biotin) - LS-C215936 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (N-Terminus) - LS-C151323 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234, FITC) - LS-C215937 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234, Azide-free, HRP) - LS-C215938 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234, PE) - LS-C215939 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa206-234) - LS-C323260 from LifeSpan Bioscience
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Anti-NDOR1 Antibody - LS-C333484 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (aa207-234) - LS-C158370 from LifeSpan Bioscience
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Anti-NDOR1 Antibody (clone 2G4) - LS-C174416 from LifeSpan Bioscience
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NDOR1 Antibody - NBP1-88790 from Novus Biologicals
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NDOR1 Antibody (3A11) - H00027158-M01 from Novus Biologicals
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NDOR1 Antibody - NBP2-19498 from Novus Biologicals
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NDOR1 Antibody (3A11) - H00027158-M01A from Novus Biologicals
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NDOR1 Antibody - H00027158-B01 from Novus Biologicals
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