Gene Symbol | NDOR1 |
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Entrez Gene | 27158 |
Alt Symbol | NR1, bA350O14.9 |
Species | Human |
Gene Type | protein-coding |
Description | NADPH dependent diflavin oxidoreductase 1 |
Other Description | NADPH-dependent FMN and FAD-containing oxidoreductase|NADPH-dependent diflavin oxidoreductase 1 |
Swissprots | Q96BC6 D3YTH9 Q5VSG4 Q9UHB4 D3YTG6 Q86US9 |
Accessions | EAW88366 Q9UHB4 AF199509 AAF25205 AK026089 AK074403 AK225995 AK290026 BAF82715 AL133632 AY077845 AAL77754 BC015735 AAH15735 BC078668 BC093782 AAH93782 BC111943 AAI11944 BC143229 DA408370 DA858250 DQ892229 ABM83155 DQ895429 ABM86355 XM_011518545 XP_011516847 XM_011518546 XP_011516848 XM_011518547 XP_011516849 XM_011518548 XP_011516850 XR_929763 XR_929764 NM_001144026 NP_001137498 NM_001144027 NP_001137499 NM_001144028 NP_001137500 NM_014434 NP_055249 |
Function | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins (By similarity). Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. {ECO:0000255|HAMAP-Rule:MF_03178, ECO:0000269|PubMed:10625700, ECO:0000269|PubMed:20802492, ECO:0000269|PubMed:23596212}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000255|HAMAP-Rule:MF_03178, ECO:0000269|PubMed:10625700, ECO:0000269|PubMed:12871939}. Note=Concentrated in perinuclear structure. |
Tissue Specificity | Low expression in brain, heart, kidney, pancreas, prostate and skeletal muscle. Highest levels in the placenta. Expressed in cancer cell lines including promyelocytic leukemia, HeLaS3, chronic myelagenous leukemia, lymphoblastic leukemia, Burkitt's lymphoma, colorectal adenocarcinoma, lung carcinoma, and melanoma G-361. {ECO:0000269|PubMed:12871939}. |
Human NDOR1 full length protein - ab162101 from Abcam
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Human NDOR1 full length protein - ab162102 from Abcam
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Human NDOR1 protein fragment - ab162103 from Abcam
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NDOR1 Antibody Blocking Peptide - LS-E4997 from LifeSpan Bioscience
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NDOR1 Antibody Blocking Peptide - LS-E20297 from LifeSpan Bioscience
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Recombinant Human NDOR1 Protein - H00027158-Q01 from Novus Biologicals
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Recombinant Human NDOR1 Protein - H00027158-P01 from Novus Biologicals
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Recombinant Human NDOR1 Protein - H00027158-P02 from Novus Biologicals
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NDOR1-Antibody-Center-Blocking-Peptide - BP17396c from Abgent, a WuXi AppTec company
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NR1 peptide - orb73047 from Biorbyt
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NDOR1 - H00027158-P01-10 from Acris Antibodies
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NDOR1 - H00027158-P01-25 from Acris Antibodies
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NDOR1 - H00027158-P02 from Acris Antibodies
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NDOR1 - H00027158-P02-10 from Acris Antibodies
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NDOR1 - H00027158-P02-25 from Acris Antibodies
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NDOR1 - H00027158-Q01-10 from Acris Antibodies
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NDOR1 - H00027158-Q01-25 from Acris Antibodies
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NDOR1 fusion protein - Ag1909 from Proteintech Group
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Recombinant Human NDOR1, GST-tagged - NDOR1-1220H from Creative Biomart
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Recombinant Human NADPH-dependent diflavin oxidoreductase 1(NDOR1) - CSB-YP883387HU CSB-EP883387HU CSB-BP883387HU CSB-MP883387HU from Cusabio
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NDOR1 (transcript variant 2) - TP304845 from Acris Antibodies
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NDOR1 Recombinant Protein Antigen - NBP1-88790PEP from Novus Biologicals
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NDOR1 Peptide, Human - M34GP10217H from Creative Peptides
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NR1 peptide - orb73045 from Biorbyt
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NADPH-dependent diflavin oxidoreductase 1 (NDOR1), Recombinant Protein - MBS1375935 from MyBioSource
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