Gene Symbol | Lep |
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Entrez Gene | 16846 |
Alt Symbol | ob, obese |
Species | Mouse |
Gene Type | protein-coding |
Description | leptin |
Other Description | obesity factor |
Swissprots | P41160 |
Accessions | AAA64213 EDL13794 EDL13795 P41160 AK030984 BAC27202 AK142589 BAE25117 BC038162 BC125245 AAI25246 FJ374142 ACJ09173 HQ166716 ADM72802 U18812 AAA64564 XM_006504999 XP_006505062 NM_008493 NP_032519 |
Function | May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. |
Subcellular Location | Secreted {ECO:0000305}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Adipocytokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway |
Leptin/OB Recombinant Protein - P4604 from Novus Biologicals
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Leptin/OB Recombinant Protein - P4527 from Novus Biologicals
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Leptin/OB Protein - NBP1-99142 from Novus Biologicals
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Leptin/OB Protein - NBP1-99357 from Novus Biologicals
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Leptin/OB Protein - NBP1-99645 from Novus Biologicals
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Leptin/OB Recombinant Protein - P4327 from Novus Biologicals
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Leptin-116-130-mouse - SP3094b from Abgent, a WuXi AppTec company
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Leptin-116-130-mouse - SP3094a from Abgent, a WuXi AppTec company
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Leptin-116-130-amide-mouse - SP3093b from Abgent, a WuXi AppTec company
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Leptin-116-130-amide-mouse - SP3093a from Abgent, a WuXi AppTec company
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Leptin protein - GTX29750 from GeneTex
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Leptin recombinant protein - GTX65363 from GeneTex
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Leptin Recombinant Protein (Active) - GTX48298-PRO from GeneTex
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Leptin Protein (OPPA00614) - OPPA00614 from Aviva Systems Biology
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Leptin Protein (OPPA01643) - OPPA01643 from Aviva Systems Biology
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LEPTIN Recombinant Protein (OPSA11091) - OPSA11091 from Aviva Systems Biology
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Leptin protein - orb97814 from Biorbyt
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Leptin protein - orb97809 from Biorbyt
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Leptin protein - 30R-2360 from Fitzgerald
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Mouse Leptin protein - 30R-1100 from Fitzgerald
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Leptin (116-130) Peptide - abx064580 from Abbexa
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Mouse Leptin Protein - abx067742 from Abbexa
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Mouse Leptin Protein (Recombinant) - abx060809 from Abbexa
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Leptin (recombinant) - AR50010PU-N from Acris Antibodies
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Leptin (recombinant) - AR50010PU-S from Acris Antibodies
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