PAM

Gene Symbol	PAM
Entrez Gene	5066
Alt Symbol	PAL, PHM
Species	Human
Gene Type	protein-coding
Description	peptidylglycine alpha-amidating monooxygenase
Other Description	pancreatic peptidylglycine alpha-amidating monooxygenase|peptidyl alpha-amidating enzyme|peptidyl-alpha-hydroxyglycine alpha-amidating lyase|peptidyl-glycine alpha-amidating monooxygenase|peptidylamidoglycolate lyase|peptidylglycine 2-hydroxylase|peptidylglycine alpha-hydroxylating monooxygenase
Swissprots	O43211 Q16252 Q8WVC7 Q86U53 Q16253 A6NMR0 O95080 Q54A45 Q9UCG0 P19021 A8K293
Accessions	CBX47438 CBX47439 CBX47440 CBX47441 EAW49084 EAW49085 EAW49086 EAW49087 EAW49088 EAW49089 EAW49090 EAW49091 EAW49092 P19021 AB095007 BAC22594 AF010472 AAD01439 AF035320 AAB88190 AK290158 BAF82847 AK296521 BAG59152 BC018127 AAH18127 BI966687 BT007419 AAP36087 DA240822 M37721 AAA36414 S75037 AAB32775 S75038 AAB32776 U19965 AAB91431 U19966 AAB91432 XM_006714632 XP_006714695 XM_006714634 XP_006714697 XM_006714636 XP_006714699 XM_006714638 XP_006714701 XM_006714639 XP_006714702 XM_006714640 XP_006714703 XM_011543418 XP_011541720 XM_011543419 XP_011541721 XM_011543420 XP_011541722 XM_011543421 XP_011541723 XM_011543422 XP_011541724 XM_011543423 XP_011541725 XM_011543424 XP_011541726 XM_011543425 XP_011541727 XM_011543426 XP_011541728 XM_011543427 XP_011541729 XR_948263 XR_948264 XR_948265 XR_948266 NM_000919 NP_000910 NM_001177306 NP_001170777 NM_138766 NP_620121 NM_138821 NP_620176 NM_138822 NP_620177 NR_033440
Function	Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
Subcellular Location	Isoform 3: Secreted. Note=Secreted from secretory granules.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAM (F-4) - sc-514110 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

PAM (S-16) - sc-17393 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-PAM antibody - ab105069 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAM antibody - ab77592 from Abcam Prices $370.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-PAM antibody [EPR2643(2)] - ab109175 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR2643(2)

Anti-PAM antibody - C-terminal - ab166729 from Abcam Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (aa21-817) - LS-C74048 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-PAL / PAM Antibody (aa200-250) - LS-C288609 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (aa2425-2475) - LS-C288610 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (aa467-901) - LS-C311609 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (aa28-352) - LS-C311844 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (aa948-960) - LS-C61775 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-PAL / PAM Antibody (aa146-195) - LS-C80574 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (C-Terminus) - LS-C201447 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-PAL / PAM Antibody (C-Terminus, clone EPR2643(2)) - LS-C138398 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR2643(2)

Anti-Peptide Histidine-Methionine / PHM Antibody - LS-C74247 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-Peptide Histidine-Methionine / PHM Antibody - LS-C343764 from LifeSpan Bioscience Prices $405.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody - AF4837 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody - NBP2-34075 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Peptidylglycine alpha-Amidating Monooxygenase/PAM Antibody - NBP1-69318 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAM antibody produced in rabbit - SAB2101711 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PAM/PAL antibody produced in goat - SAB2500745 from Sigma-Aldrich Prices $376.00 Sizes 100 µg Host Goat Clonality Polyclonal

PAM antibody - N-terminal region (ARP43512_P050) - ARP43512_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PAM--PAL-Antibody - AF1782a from Abgent, a WuXi AppTec company Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

PAM antibody, C-term - GTX88835 from GeneTex Prices $329.00 Sizes 100 μg Host Goat Clonality Polyclonal

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