CIRBP

Gene Symbol	CIRBP
Entrez Gene	1153
Alt Symbol	CIRP
Species	Human
Gene Type	protein-coding
Description	cold inducible RNA binding protein
Other Description	A18 hnRNP|cold inducible RNA-binding protein|cold-inducible RNA-binding protein|glycine-rich RNA binding protein
Swissprots	B3KT17 Q14011 B4E2X2
Accessions	AAC04895 CBB98487 EAW69520 EAW69521 EAW69522 EAW69523 EAW69524 EAW69525 Q14011 AB451225 BAG70039 AB451348 BAG70162 AF021336 AAC51787 AK094781 BAG52929 AK095781 AK128423 BAC87434 AK304185 BAG65065 AK304470 BAG65284 AK311601 AL133636 BC000403 AAH00403 BC000901 AAH00901 BI819825 BM706055 BP195090 BT007210 AAP35874 BU689520 CX785176 D78134 BAA11212 DA433715 DA695021 EU176219 ABW03670 EU176522 ABW03323 XM_006722637 XP_006722700 XM_011527668 XP_011525970 NM_001280 NP_001271 NM_001300815 NP_001287744 NM_001300829 NP_001287758 NR_023312 NR_023313
Function	Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. {ECO:0000250, ECO:0000269|PubMed:11574538, ECO:0000269|PubMed:16513844}.
Subcellular Location	Nucleus, nucleoplasm {ECO:0000269|PubMed:11574538}. Cytoplasm {ECO:0000269|PubMed:11574538}. Note=Translocates from the nucleus to the cytoplasm after exposure to UV radiation. Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins (By similarity). {ECO:0000250}.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CIRBP full length protein - ab116730 from Abcam Category Protein Source Wheat germ Species Human

Human CIRBP full length protein - ab106903 from Abcam Category Protein Source E. coli Species Human

Human CIRBP protein fragment - ab116731 from Abcam Category Protein Source Wheat germ Species Human

CIRP / CIRBP Antibody Blocking Peptide - LS-E14702 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIRP / CIRBP Antibody Blocking Peptide - LS-E27439 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIRP / CIRBP Antibody Blocking Peptide - LS-E27440 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIRP / CIRBP Antibody Blocking Peptide - LS-E9962 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CIRBP Recombinant Protein - H00001153-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

CIRBP Partial Recombinant Protein - H00001153-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CIRBP Recombinant Protein - H00001153-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CIRBP Protein - NBP1-51095 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CIRBP-Antibody-C-term-Blocking-Peptide - BP9139b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CIRBP Blocking Peptide - 33R-3676 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CIRBP Blocking Peptide - 33R-5739 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CIRBP protein (His tag) - 80R-1790 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

CIRBP Peptide - AC21-2264-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CIRBP Peptide - AC21-2265-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CIRBP (1-172, His-tag) - AR09973PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CIRBP (1-172, His-tag) - AR09973PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CIRBP - H00001153-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

CIRBP - H00001153-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CIRBP - H00001153-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CIRBP - H00001153-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CIRBP - H00001153-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CIRBP - H00001153-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

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