Gene Symbol | EID2 |
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Entrez Gene | 163126 |
Alt Symbol | CRI2, EID-2 |
Species | Human |
Gene Type | protein-coding |
Description | EP300 interacting inhibitor of differentiation 2 |
Other Description | CREBBP/EP300 inhibitor 2|CREBBP/EP300 inhibitory protein 2|E1A like inhibitor of differentiation 2|EID-1-like inhibitor of differentiation 2|EP300-interacting inhibitor of differentiation 2 |
Swissprots | Q6ZR61 Q6X7T0 A7YQ71 Q8N6I1 |
Accessions | EAW56909 Q8N6I1 AK128468 BAC87454 AY251272 AAP12559 BC030137 AAH30137 BC099899 AAH99899 NM_153232 NP_694964 |
Function | Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex. {ECO:0000269|PubMed:12586827, ECO:0000269|PubMed:14585496, ECO:0000269|PubMed:14612439}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14585496}. |
Tissue Specificity | Most abundantly expressed in placenta. Highly expressed in liver, brain, heart, skeletal muscle, and kidney. {ECO:0000269|PubMed:14585496}. |
EID2 Antibody Blocking Peptide - LS-E7913 from LifeSpan Bioscience
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EID2 Antibody Blocking Peptide - LS-E19170 from LifeSpan Bioscience
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EID2-Antibody-C-term-Blocking-peptide - BP5633b from Abgent, a WuXi AppTec company
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Recombinant Human EP300-interacting inhibitor of differentiation 2(EID2) - CSB-YP854053HU CSB-EP854053HU CSB-BP854053HU CSB-MP854053HU from Cusabio
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EID2 Recombinant Protein Antigen - NBP1-94096PEP from Novus Biologicals
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EID2 Peptide, Human - M34GP04788H from Creative Peptides
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EP300-interacting inhibitor of differentiation 2 (EID2), Recombinant Protein - MBS1484487 from MyBioSource
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