Gene Symbol | MED27 |
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Entrez Gene | 9442 |
Alt Symbol | CRAP34, CRSP34, CRSP8, TRAP37 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 27 |
Other Description | CRSP complex subunit 8|cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa|mediator of RNA polymerase II transcription subunit 27|p37 TRAP/SMCC/PC2 subunit|transcriptional coactivator CRSP34 |
Swissprots | Q5VTA5 Q9BU57 V9GYV9 Q4F964 O95401 Q9NYR4 Q6P2C8 Q5VTA4 |
Accessions | EAW87989 EAW87990 EAW87991 EAW87992 EAW87993 Q6P2C8 AF104252 AAD12721 AF230382 AAF37290 AI033804 AK022289 AK124232 AK298436 BAG60657 AK316345 BAH14716 BC002878 AAH02878 BC064608 AAH64608 BC070331 BP255072 BU069864 CD388680 DQ099387 AAZ13763 EU446747 ABZ92276 HG518166 CDI06889 Z36848 XM_005272236 XP_005272293 NM_001253881 NP_001240810 NM_001253882 NP_001240811 NM_004269 NP_004260 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:10882111, ECO:0000269|PubMed:9989412}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10882111, ECO:0000269|PubMed:9989412}. |
Human CRSP8 full length protein - ab160491 from Abcam
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Human CRSP8 full length protein - ab180327 from Abcam
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MED27 / CRSP8 Antibody Blocking Peptide - LS-E11933 from LifeSpan Bioscience
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MED27 / CRSP8 Antibody Blocking Peptide - LS-E13813 from LifeSpan Bioscience
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MED27 Recombinant Protein - H00009442-P01 from Novus Biologicals
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MED27 protein (His tag) - 80R-3783 from Fitzgerald
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MED27 (1-311, His-tag) - AR51470PU-N from Acris Antibodies
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MED27 (1-311, His-tag) - AR51470PU-S from Acris Antibodies
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MED27 - H00009442-P01-10 from Acris Antibodies
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MED27 - H00009442-P01-25 from Acris Antibodies
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MED27, 1-311aa, Human, His tag, E.coli - 01-P2650 from ARP American Research Products
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MED27 fusion protein - ag12046 from Proteintech Group
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MED27 fusion protein - ag11897 from Proteintech Group
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Recombinant Human MED27, His-tagged - MED27-157H from Creative Biomart
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Recombinant Human Mediator of RNA polymerase II transcription subunit 27(MED27) - CSB-YP764716HU CSB-EP764716HU CSB-BP764716HU CSB-MP764716HU from Cusabio
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MED27, 1-311aa, Human, His tag, E.coli (Denatured) - ATGP2650 from ATGen
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Mediator Complex Subunit 27 Protein (Recombinant) - abx262762 from Abbexa
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Human MED27 protein - orb259962 from Biorbyt
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MED27 Recombinant Protein Antigen - NBP1-84377PEP from Novus Biologicals
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CRSP8 Blocking Peptide - abx161943 from Abbexa
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CRSP8-Antibody-Center-Blocking-Peptide - BP7432c from Abgent, a WuXi AppTec company
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MED27 Peptide, Human - M34GP09372H from Creative Peptides
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CRSP8 Blocking Peptide - CBP4732 from Cohesion Biosciences
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Recombinant Human MED27 Protein - NBP2-51663 from Novus Biologicals
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MED27 - PAT-82649-1 from Nordic BioSite
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