CITED4

Gene Symbol	CITED4
Entrez Gene	163732
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
Other Description	MRG-2|MSG1-related protein 2|cbp/p300-interacting transactivator 4|transcriptional co-activator 4
Swissprots	Q96RK1
Accessions	AAK64235 AAL73989 CAN89457 CAN89458 CAP11404 CAP11405 EAX07195 Q96RK1 BC035496 AAH35496 BC052559 AAH52559 NM_133467 NP_597724
Function	Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells. {ECO:0000269|PubMed:11744733, ECO:0000269|PubMed:15342390}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11744733, ECO:0000269|PubMed:15342390}. Cytoplasm {ECO:0000269|PubMed:11744733, ECO:0000269|PubMed:15342390}.
Tissue Specificity	Expressed in most tissues examined with highest levels of expression in heart, liver, skeletal muscle and pancreas. Also expressed in bladder cell line ECV-304 and in various breast cancer cell lines. Also detected in both in situ and invasive breast tumors where its expression is down-regulated and mostly restricted to the cytoplasm of malignant epithelium. Down-regulation of expression is associated with elevated levels of HIF1A and increased tumor growth and angiogenesis. {ECO:0000269|PubMed:11744733, ECO:0000269|PubMed:15342390}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CITED4 protein fragment - ab153612 from Abcam Category Protein Source Wheat germ Species Human

CITED4 Antibody Blocking Peptide - LS-E13357 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CITED4 Antibody Blocking Peptide - LS-E13356 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CITED4 Protein - H00163732-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Cited4 Blocking Peptide - 33R-7269 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CITED4 Blocking Peptide - 33R-7440 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CITED4 - H00163732-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CITED4 - H00163732-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Recombinant Human Cbp/p300-interacting transactivator 4(CITED4) - CSB-YP842752HU CSB-EP842752HU CSB-BP842752HU CSB-MP842752HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Cbp/p300-interacting transactivator 4 (CITED4), Recombinant Protein - MBS1380220 from MyBioSource Category Protein Prices $930.00, $930.00, $1,155.00, $1,155.00, $1,390.00, $1,390.00, $1,845.00, $1,845.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CITED4 Recombinant Protein Antigen - NBP2-33788PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CITED4 Peptide, Human - M34GP03190H from Creative Peptides Category Peptide Source Synthetic. Species Human

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