| Gene Symbol |
UBTF
|
| Entrez Gene |
7343
|
| Alt Symbol |
NOR-90, UBF, UBF-1, UBF1, UBF2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
upstream binding transcription factor, RNA polymerase I
|
| Other Description |
90-kDa nucleolus organizer region autoantigen|autoantigen NOR-90|nucleolar transcription factor 1
|
| Swissprots |
A8K6R8 P17480
|
| Accessions |
AAC51239 CAC34632 EAW51616 EAW51617 EAW51618 EAW51619 EAW51620 P17480 AF289595 AAL55779 AK291733 BAF84422 AK292518 BAF85207 AK292577 BAF85266 AK296917 BAG59472 AK298008 BAG60313 AK308321 BC031423 AAH31423 BC042297 AAH42297 BP230502 DR000113 M61724 X53390 CAA37469 X53461 CAA37548 X56687 CAA40016 XM_006722059 XP_006722122 XM_006722060 XP_006722123 XM_006722061 XP_006722124 XM_011525177 XP_011523479 NM_001076683 NP_001070151 NM_001076684 NP_001070152 NM_014233 NP_055048 NR_045058
|
| Function |
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. {ECO:0000269|PubMed:7982918}.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000250}.
|
![Western Blot: UBTF Overexpression Lysate (Adult Normal) [NBP2-09253] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UBTF.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10704_UBTF%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09253-img0001.jpg)