Gene Symbol | UBTF |
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Entrez Gene | 7343 |
Alt Symbol | NOR-90, UBF, UBF-1, UBF1, UBF2 |
Species | Human |
Gene Type | protein-coding |
Description | upstream binding transcription factor, RNA polymerase I |
Other Description | 90-kDa nucleolus organizer region autoantigen|autoantigen NOR-90|nucleolar transcription factor 1 |
Swissprots | A8K6R8 P17480 |
Accessions | AAC51239 CAC34632 EAW51616 EAW51617 EAW51618 EAW51619 EAW51620 P17480 AF289595 AAL55779 AK291733 BAF84422 AK292518 BAF85207 AK292577 BAF85266 AK296917 BAG59472 AK298008 BAG60313 AK308321 BC031423 AAH31423 BC042297 AAH42297 BP230502 DR000113 M61724 X53390 CAA37469 X53461 CAA37548 X56687 CAA40016 XM_006722059 XP_006722122 XM_006722060 XP_006722123 XM_006722061 XP_006722124 XM_011525177 XP_011523479 NM_001076683 NP_001070151 NM_001076684 NP_001070152 NM_014233 NP_055048 NR_045058 |
Function | Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. {ECO:0000269|PubMed:7982918}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000250}. |
UBF CRISPR/Cas9 KO Plasmid (h) - sc-400521 from Santa Cruz Biotechnology
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UBF HDR Plasmid (h) - sc-400521-HDR from Santa Cruz Biotechnology
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UBF Double Nickase Plasmid (h) - sc-400521-NIC from Santa Cruz Biotechnology
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UBF Double Nickase Plasmid (h2) - sc-400521-NIC-2 from Santa Cruz Biotechnology
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UBF CRISPR Activation Plasmid (h) - sc-400521-ACT from Santa Cruz Biotechnology
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UBF CRISPR Activation Plasmid (h2) - sc-400521-ACT-2 from Santa Cruz Biotechnology
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UBF Lentiviral Activation Particles (h) - sc-400521-LAC from Santa Cruz Biotechnology
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UBF Lentiviral Activation Particles (h2) - sc-400521-LAC-2 from Santa Cruz Biotechnology
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UBF siRNA (h) - sc-29514 from Santa Cruz Biotechnology
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UBF1 shRNA Plasmid (h) - sc-29514-SH from Santa Cruz Biotechnology
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UBF1 shRNA (h) Lentiviral Particles - sc-29514-V from Santa Cruz Biotechnology
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UBTF RNAi - H00007343-R01 from Novus Biologicals
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MISSION® esiRNA - EHU085111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22422 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22422 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11258 from Sigma-Aldrich
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UBTF siRNA (Human) - CRH5020 from Cohesion Biosciences
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UBTF - MBS8240031 from MyBioSource
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shRNA set against Human UBTF (NM_014233.3) - SHH439612 from Creative biogene
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shRNA set against Human UBTF(NM_001076683.1) - SHL104106 from Creative biogene
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UBF CRISPR/Cas9 KO Plasmid (h2) - sc-400521-KO-2 from Santa Cruz Biotechnology
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UBF HDR Plasmid (h2) - sc-400521-HDR-2 from Santa Cruz Biotechnology
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Human UBTF siRNA - orb265522 from Biorbyt
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UBTF shRNA Plasmid (Human) - CHH5020 from Cohesion Biosciences
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UBTF miRNA 3'UTR clone - MiUTR1H-10970 from Creative biogene
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