Gene Symbol | BHLHE22 |
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Entrez Gene | 27319 |
Alt Symbol | BHLHB5, Beta3, CAGL85, TNRC20 |
Species | Human |
Gene Type | protein-coding |
Description | basic helix-loop-helix family, member e22 |
Other Description | basic helix-loop-helix domain containing, class B, 5|class B basic helix-loop-helix protein 5|class E basic helix-loop-helix protein 22|trinucleotide repeat containing 20|trinucleotide repeat-containing gene 20 protein |
Swissprots | Q8NFJ8 |
Accessions | AAM28881 EAW86876 Q8NFJ8 AA927689 AI867692 AI968349 AK091333 AK293979 BAG57349 AW206610 BC033056 BC045748 BC156671 AAI56672 BK000273 DAA01053 NM_152414 NP_689627 |
Function | Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Brain-specific, with the highest expression in the cerebellum. {ECO:0000269|PubMed:12213201}. |
BHLHB5 peptide - ab109071 from Abcam
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BHLHE22 / BHLHB5 Antibody Blocking Peptide - LS-E7586 from LifeSpan Bioscience
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BHLHE22 / BHLHB5 Antibody Blocking Peptide - LS-E11357 from LifeSpan Bioscience
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BHLHB5-Antibody-Center-Blocking-Peptide - BP4777c from Abgent, a WuXi AppTec company
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BHLHE22 fusion protein - Ag20966 from Proteintech Group
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Recombinant Human Class E basic helix-loop-helix protein 22(BHLHE22) - CSB-YP847705HU CSB-EP847705HU CSB-BP847705HU CSB-MP847705HU from Cusabio
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BHLHB5 Protein - NBP2-39085PEP from Novus Biologicals
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BHLHB5 Recombinant Protein Antigen - NBP2-39039PEP from Novus Biologicals
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BHLHB5 Recombinant Protein Antigen - NBP2-39016PEP from Novus Biologicals
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BHLHE22 Peptide, Human - M34GP01430H from Creative Peptides
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Class E basic helix-loop-helix protein 22 (BHLHE22), Recombinant Protein - MBS1422383 from MyBioSource
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