Gene Symbol | BHLHE22 |
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Entrez Gene | 27319 |
Alt Symbol | BHLHB5, Beta3, CAGL85, TNRC20 |
Species | Human |
Gene Type | protein-coding |
Description | basic helix-loop-helix family, member e22 |
Other Description | basic helix-loop-helix domain containing, class B, 5|class B basic helix-loop-helix protein 5|class E basic helix-loop-helix protein 22|trinucleotide repeat containing 20|trinucleotide repeat-containing gene 20 protein |
Swissprots | Q8NFJ8 |
Accessions | AAM28881 EAW86876 Q8NFJ8 AA927689 AI867692 AI968349 AK091333 AK293979 BAG57349 AW206610 BC033056 BC045748 BC156671 AAI56672 BK000273 DAA01053 NM_152414 NP_689627 |
Function | Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Brain-specific, with the highest expression in the cerebellum. {ECO:0000269|PubMed:12213201}. |
BETA 3 (K-18) - sc-6046 from Santa Cruz Biotechnology
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BETA 3 (E-17) - sc-6045 from Santa Cruz Biotechnology
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Anti-BHLHB5 antibody - ab95136 from Abcam
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Anti-BHLHB5 antibody - ab49315 from Abcam
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Anti-BHLHB5 antibody - ab167186 from Abcam
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Anti-BHLHE22 / BHLHB5 Antibody (aa139-156) - LS-C149027 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272, AP) - LS-C233151 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa119-168) - LS-C30910 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa119-168) - LS-C29835 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272, APC) - LS-C233152 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272, Biotin) - LS-C233153 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272, FITC) - LS-C233154 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272, PE) - LS-C233155 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272, Azide-free, HRP) - LS-C249524 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa243-272) - LS-C319838 from LifeSpan Bioscience
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Anti-BHLHE22 / BHLHB5 Antibody (aa236-264) - LS-C156810 from LifeSpan Bioscience
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BHLHB5 Antibody - NBP2-39016 from Novus Biologicals
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BHLHB5 Antibody - NBP2-39085 from Novus Biologicals
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BHLHB5 Antibody - NBP2-39039 from Novus Biologicals
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BHLHB5 Antibody - H00027319-B01P-50ug from Novus Biologicals
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BHLHB5 Polyclonal Antibody - bs-11808R from Bioss
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BHLHB5 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11808R-A350 from Bioss
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BHLHB5 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11808R-A488 from Bioss
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BHLHB5 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11808R-A555 from Bioss
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BHLHB5 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11808R-A647 from Bioss
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