Gene Symbol | CAPN1 |
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Entrez Gene | 823 |
Alt Symbol | CANP, CANP1, CANPL1, muCANP, muCL |
Species | Human |
Gene Type | protein-coding |
Description | calpain 1, (mu/I) large subunit |
Other Description | CANP 1|calcium-activated neutral proteinase 1|calpain mu-type|calpain, large polypeptide L1|calpain-1 catalytic subunit|calpain-1 large subunit|cell proliferation-inducing gene 30 protein|cell proliferation-inducing protein 30|micromolar-calpain |
Swissprots | Q2TTR0 Q6DHV4 P07384 |
Accessions | AAV41878 EAW74366 EAW74367 EAW74368 EAW74369 EAW74370 EAW74371 P07384 AK022319 AK025380 AK097277 AK301538 BAG63037 AK311001 AK315556 BAG37932 AY550975 AAT52221 BC008751 AAH08751 BC015091 BC017200 AAH17200 BC075862 AAH75862 BE018156 DA788342 DC365116 DC372552 DQ892905 ABM83831 DQ896600 ABM87599 X04366 CAA27881 XM_006718698 XP_006718761 XM_011545292 XP_011543594 NM_001198868 NP_001185797 NM_001198869 NP_001185798 NM_005186 NP_005177 NR_040008 |
Function | Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:8769305}. Cell membrane {ECO:0000269|PubMed:8769305}. Note=Translocates to the plasma membrane upon Ca(2+) binding. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Apoptosis, Alzheimer's disease, Protein processing in endoplasmic reticulum |
Active human Calpain 1 full length protein - ab91019 from Abcam
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Active pig Calpain 1 full length protein - ab198675 from Abcam
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Calpain 1 peptide - ab41299 from Abcam
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Calpain 1 peptide - ab41300 from Abcam
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Calpain 1 peptide - ab41301 from Abcam
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CAPN1 / Calpain 1 Antibody Blocking Peptide - LS-E22288 from LifeSpan Bioscience
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CAPN1 / Calpain 1 Antibody Blocking Peptide - LS-E22287 from LifeSpan Bioscience
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CAPN1 / Calpain 1 Antibody Blocking Peptide - LS-E28054 from LifeSpan Bioscience
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CAPN1 / Calpain 1 Antibody Blocking Peptide - LS-E28055 from LifeSpan Bioscience
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Calpain 1 Partial Recombinant Protein - H00000823-Q01 from Novus Biologicals
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Calpain 1 Human Expressed Protein - P4041 from Novus Biologicals
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CAPN1 - Human Calpain-1 Catalytic Subunit Protein (OPPA01276) - OPPA01276 from Aviva Systems Biology
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Human CAPN1 protein - orb244068 from Biorbyt
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Human Calpain-1 Catalytic Subunit protein - orb80996 from Biorbyt
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CAPN1 Blocking Peptide - 33R-2417 from Fitzgerald
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CAPN1 Blocking Peptide - 33R-2781 from Fitzgerald
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Human CAPN1 Protein - abx065675 from Abbexa
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Human CAPN1 Protein - abx065670 from Abbexa
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Calpain 1 Peptide - AC21-2924-P from Abcore
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Calpain 1 Peptide - AC21-2925-P from Abcore
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Calpain-1 - H00000823-Q01-10 from Acris Antibodies
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Calpain-1 - H00000823-Q01-25 from Acris Antibodies
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Calpain-1 - P4041 from Acris Antibodies
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Human Calpain-1 Catalytic Subunit - 228-10169-1 from RayBiotech
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Native Human CAPN1 - 228-10169-2 from RayBiotech
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