FBXO32

Gene Symbol	FBXO32
Entrez Gene	114907
Alt Symbol	Fbx32, MAFbx
Species	Human
Gene Type	protein-coding
Description	F-box protein 32
Other Description	F-box only protein 32|atrogin 1|atrogin-1|muscle atrophy F-box protein
Swissprots	Q969P5 A4KYM0
Accessions	EAW92040 EAW92041 EAW92042 EAW92043 Q969P5 AI077844 AJ420108 CAD12251 AK023391 AK056986 BAB71333 AK096904 AK124390 AK125888 AY059629 AAL16407 BC022416 BC024030 AAH24030 BC100020 AAI00021 BC120963 AAI20964 BC120964 AAI20965 DB503484 EF143260 ABO37797 HQ447898 ADQ32382 NM_001242463 NP_001229392 NM_058229 NP_478136 NM_148177 NP_680482
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. {ECO:0000269|PubMed:15531760}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:22249105}. Nucleus {ECO:0000269|PubMed:22249105}. Note=Shuttles between Cytoplasm and the nucleus.
Tissue Specificity	Specifically expressed in cardiac and skeletal muscle.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MAFbx CRISPR/Cas9 KO Plasmid (h) - sc-400908 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx HDR Plasmid (h) - sc-400908-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx Double Nickase Plasmid (h) - sc-400908-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx Double Nickase Plasmid (h2) - sc-400908-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx CRISPR Activation Plasmid (h) - sc-400908-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx CRISPR Activation Plasmid (h2) - sc-400908-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx Lentiviral Activation Particles (h) - sc-400908-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx Lentiviral Activation Particles (h2) - sc-400908-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx siRNA (h) - sc-43906 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MAFbx shRNA Plasmid (h) - sc-43906-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MAFbx shRNA (h) Lentiviral Particles - sc-43906-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU155831 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8549 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8549 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02549 from Sigma-Aldrich Category miRNA

FBXO32 siRNA (Human) - CRJ4414 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FBXO32 - MBS8226361 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MAFbx CRISPR/Cas9 KO Plasmid (h2) - sc-400908-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MAFbx HDR Plasmid (h2) - sc-400908-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human FBXO32 (NM_058229.3) - SHH293217 from Creative biogene Category siRNA Species Reactivities Human

Human FBXO32 siRNA - orb274915 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FBXO32 shRNA Plasmid (Human) - CHJ4414 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

FBXO32 miRNA 3'UTR clone - MiUTR3H-08602 from Creative biogene Species Reactivities Human

FBXO32 miRNA 3'UTR clone - MiUTR3H-08603 from Creative biogene Species Reactivities Human

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