RXFP1

Gene Symbol RXFP1
Entrez Gene 59350
Alt Symbol LGR7, RXFPR1
Species Human
Gene Type protein-coding
Description relaxin/insulin-like family peptide receptor 1
Other Description leucine-rich repeat-containing G protein-coupled receptor 7|relaxin receptor 1
Swissprots Q3KU25 Q9HBX9 Q2M215 Q3KU26 B4DTV2 B4DHD1 Q3KU24
Accessions AAY41039 EAX04856 EAX04857 Q9HBX9 AB208943 BAD92180 AF190500 AAG17167 AI653269 AK122647 BAG53639 AK294694 BAG57853 AK295040 BAG58092 AK300379 BAG62114 AK307889 AK312470 AY899848 AAX85196 AY899849 AAX85197 AY899850 AAX85198 BC112142 AAI12143 BC113617 AAI13618 BC143556 BC143557 BC143558 BC143559 BX647975 BX647980 BX647985 CR748189 DA156504 DA241507 DA308373 DA519897 DC334052 HQ258496 ADR83250 XM_011532174 XP_011530476 XM_011532175 XP_011530477 XM_011532176 XP_011530478 XM_011532177 XP_011530479 XM_011532178 XP_011530480 XM_011532179 XP_011530481 NM_001253727 NP_001240656 NM_001253728 NP_001240657 NM_001253729 NP_001240658 NM_001253730 NP_001240659 NM_001253732 NP_001240661 NM_001253733 NP_001240662 NM_021634 NP_067647 NR_045579 NR_045580 NR_045581 NR_045582 NR_045583 NR_045584
Function Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16051677}; Multi-pass membrane protein {ECO:0000269|PubMed:16051677}.
Tissue Specificity Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen. {ECO:0000269|PubMed:16051677}.
Top Pathways Neuroactive ligand-receptor interaction

Relaxin Receptor 1 (H-160) - sc-50328 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Relaxin Receptor 1 (H-160): sc-50328. Western blot analysis of Relaxin Receptor 1 expression in THP-1 whole cell lysate.

Relaxin Receptor 1 (T-20) - sc-22009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GPCR LGR7 antibody - ab57519 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57519 GPCR LGR7 antibody at 1ug/ml.

Anti-GPCR LGR7 antibody - C-terminal - ab140903 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus endometrium tissue labelling GPCR LGR7 with ab140903 at 12µg/ml.

Anti-GPCR LGR7 antibody - C-terminal - ab156259 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GPCR LGR7 antibody - C-terminal (ab156259) at 1/100 dilution + A375 cell line lysate at 35 µg

Anti-RXFP1/ LGR7 Antibody (aa735-757) - LS-C190993 from LifeSpan Bioscience

Prices $800.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713, APC) - LS-C217360 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713, AP) - LS-C217361 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713, Biotin) - LS-C217362 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713, FITC) - LS-C217363 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713, Azide-free, HRP) - LS-C217364 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713, PE) - LS-C217365 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa110-259, Biotin) - LS-C298634 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa260-409, Biotin) - LS-C299131 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa110-259, FITC) - LS-C302790 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa260-409, FITC) - LS-C302019 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa68-163) - LS-C309177 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-RXFP1/ LGR7 Antibody (aa685-713) - LS-C330087 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXFP1/ LGR7 Antibody (aa260-409) - LS-C296214 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant RXFP1/ LGR7.

Anti-RXFP1/ LGR7 Antibody (aa110-259) - LS-C296215 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant RXFP1/ LGR7.

Anti-RXFP1/ LGR7 Antibody (aa50-100) - LS-C47303 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of human Relaxin receptor 1inhumanheart lysate in the1) absence and 2) presence of immunizing peptide using antibody at0.5 ug/ml.

Anti-RXFP1/ LGR7 Antibody (aa685-713) - LS-C156024 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RXFP1 Antibody western blot of A375 cell line lysates (35 ug/lane). The RXFP1 antibody detected the RXFP1 protein (arrow).

Anti-RXFP1/ LGR7 Antibody (N-Terminus) IHC-plus™ - LS-A566 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RXFP1 antibody LS-A566 IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-RXFP1/ LGR7 Antibody (aa694-711) IHC-plus™ - LS-B7212 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-RXFP1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7212 concentration 10 ug/ml.

Anti-RXFP1/ LGR7 Antibody (N-Terminus) IHC-plus™ - LS-A565 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RXFP1 antibody LS-A565 IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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