RXFP1

Gene Symbol	RXFP1
Entrez Gene	59350
Alt Symbol	LGR7, RXFPR1
Species	Human
Gene Type	protein-coding
Description	relaxin/insulin-like family peptide receptor 1
Other Description	leucine-rich repeat-containing G protein-coupled receptor 7|relaxin receptor 1
Swissprots	Q3KU25 Q9HBX9 Q2M215 Q3KU26 B4DTV2 B4DHD1 Q3KU24
Accessions	AAY41039 EAX04856 EAX04857 Q9HBX9 AB208943 BAD92180 AF190500 AAG17167 AI653269 AK122647 BAG53639 AK294694 BAG57853 AK295040 BAG58092 AK300379 BAG62114 AK307889 AK312470 AY899848 AAX85196 AY899849 AAX85197 AY899850 AAX85198 BC112142 AAI12143 BC113617 AAI13618 BC143556 BC143557 BC143558 BC143559 BX647975 BX647980 BX647985 CR748189 DA156504 DA241507 DA308373 DA519897 DC334052 HQ258496 ADR83250 XM_011532174 XP_011530476 XM_011532175 XP_011530477 XM_011532176 XP_011530478 XM_011532177 XP_011530479 XM_011532178 XP_011530480 XM_011532179 XP_011530481 NM_001253727 NP_001240656 NM_001253728 NP_001240657 NM_001253729 NP_001240658 NM_001253730 NP_001240659 NM_001253732 NP_001240661 NM_001253733 NP_001240662 NM_021634 NP_067647 NR_045579 NR_045580 NR_045581 NR_045582 NR_045583 NR_045584
Function	Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16051677}; Multi-pass membrane protein {ECO:0000269|PubMed:16051677}.
Tissue Specificity	Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen. {ECO:0000269|PubMed:16051677}.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GPCR LGR7 protein fragment - ab153471 from Abcam Category Protein Source Wheat germ Species Human

RXFP1/ LGR7 Antibody Blocking Peptide - LS-E29083 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

RXFP1/ LGR7 Antibody Blocking Peptide - LS-E29086 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

RXFP1/ LGR7 Antibody Blocking Peptide - LS-E29087 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Relaxin R1/LGR7 Partial Recombinant Protein - H00059350-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Relaxin R1/LGR7 Protein - H00059350-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

LGR7 blocking peptide - GTX89546-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

Recombinant Human Relaxin R1 Fc Chimera, CF - 7996-RR-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

Human RXFP1 Protein - abx068858 from Abbexa Category Protein Source E.coli Species Human

Human RXFP1 Protein - abx068859 from Abbexa Category Protein Source E.coli Species Human

Relaxin receptor 1 / RXFP1 - H00059350-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Relaxin receptor 1 / RXFP1 - H00059350-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Relaxin/Insulin Like Family Peptide Receptor 1 - 20-7728 from ARP American Research Products Category Peptide Prices $549.00 Sizes 50 µg Source E.coli Species Human

Relaxin/Insulin Like Family Peptide Receptor 1 - 20-7729 from ARP American Research Products Category Peptide Prices $521.00 Sizes 50 µg Source E.coli Species Human

RXFP1 fusion protein - ag13098 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

RXFP1 fusion protein - ag13105 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) - RPB456Hu01 from Uscn Life Science Inc. Category Peptide Source E.coli Species Human

Recombinant Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) - RPB456Hu02 from Uscn Life Science Inc. Category Peptide Source E.coli Species Human

Recombinant Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) - RPB456Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) - RPB456Hu02 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Relaxin R1 Fc Chimera Protein, CF - 7996-RR from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Human Relaxin R1 (Gln23-Ser398) Accession # Q9HBX9 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

RXFP1 Protein - abx163829 from Abbexa Category Protein Species Human

Relaxin R1/LGR7 Recombinant Protein Antigen - NBP1-89585PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RXFP1-Blocking-Peptide-C-term - BP19927B from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RXFP1 Peptide, Human - M34GP13706H from Creative Peptides Category Peptide Source Synthetic. Species Human

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