Gene Symbol | DCLRE1A |
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Entrez Gene | 9937 |
Alt Symbol | PSO2, SNM1, SNM1A |
Species | Human |
Gene Type | protein-coding |
Description | DNA cross-link repair 1A |
Other Description | DNA cross-link repair 1A protein|DNA-crosslink repair gene SNM1|SNM1 homolog A |
Swissprots | Q6PJP8 Q6P5Y3 Q14701 D3DRC1 Q6PKL4 |
Accessions | AAT09762 ABI49507 EAW49489 EAW49490 Q6PJP8 AK307187 BC013124 AAH13124 BC062582 AAH62582 D42045 BAA07646 DA456679 DB224073 H98725 XM_006718090 XP_006718153 XM_011540429 XP_011538731 NM_001271816 NP_001258745 NM_014881 NP_055696 |
Function | May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. {ECO:0000269|PubMed:15542852}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10848582, ECO:0000269|PubMed:12446782, ECO:0000269|PubMed:15572677}. Note=In some cells it may be found in typically 1 or 2 discrete nuclear aggregates of unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in number following treatment with ionizing radiation or interstrand cross- linking agents. These foci overlap with those formed by the MRN complex (composed of MRE11A, RAD50 and NBN) and BRCA1. |
Tissue Specificity | Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle. {ECO:0000269|PubMed:12446782}. |
SNM1A (D-14) - sc-160814 from Santa Cruz Biotechnology
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SNM1A (N-15) - sc-160816 from Santa Cruz Biotechnology
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SNM1A (H-155) - sc-367631 from Santa Cruz Biotechnology
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Anti-SNM1 antibody - ab176690 from Abcam
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Anti-SNM1 antibody - ab79012 from Abcam
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Anti-SNM1 antibody - ab14805 from Abcam
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Anti-DCLRE1A / SNM1 Antibody (aa397-410) IHC-plus⢠- LS-B1759 from LifeSpan Bioscience
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Anti-DCLRE1A / SNM1 Antibody (aa1032-1044) IHC-plus⢠- LS-B1758 from LifeSpan Bioscience
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Anti-DCLRE1A / SNM1 Antibody (aa425-475) - LS-C290400 from LifeSpan Bioscience
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Anti-DCLRE1A / SNM1 Antibody (aa1-50) - LS-C290399 from LifeSpan Bioscience
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SNM1 Antibody - NBP1-89663 from Novus Biologicals
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Anti-DCLRE1A antibody produced in rabbit - HPA036907 from Sigma-Aldrich
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SNM1-C-Term-Antibody-C-Term - AF2404a from Abgent, a WuXi AppTec company
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SNM1--DCLRE1A-internal-Antibody-internal-region - AF2478a from Abgent, a WuXi AppTec company
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DCLRE1A antibody - C-terminal region (OAEB00232) - OAEB00232 from Aviva Systems Biology
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Goat Anti-SNM1 / DCLRE1A (internal) Antibody (OAEB00745) - OAEB00745 from Aviva Systems Biology
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DCLRE1A Antibody (OALA02110) - OALA02110 from Aviva Systems Biology
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DCLRE1A Antibody (OALA02111) - OALA02111 from Aviva Systems Biology
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DCLRE1A antibody - PAB6624 from Acris Antibodies
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DCLRE1A antibody - PAB6923 from Acris Antibodies
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Anti-SNM1 Antibody - AC21-0546 from Abcore
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Anti-SNM1 Antibody - AC21-0831 from Abcore
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Anti-SNM1 Antibody (AMCA) - AC21-0546-01 from Abcore
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Anti-SNM1 Antibody (AMCA) - AC21-0831-01 from Abcore
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Anti-SNM1 Antibody (AP) - AC21-0546-02 from Abcore
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