CBFA2T3

Gene Symbol CBFA2T3
Entrez Gene 863
Alt Symbol ETO2, MTG16, MTGR2, ZMYND4
Species Human
Gene Type protein-coding
Description core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Other Description MTG8-related gene 2|MTG8-related protein 2|myeloid translocation gene 8 and 16b|myeloid translocation gene on chromosome 16 protein|protein CBFA2T3|zinc finger MYND domain-containing protein 4
Swissprots O60617 Q0P5Z6 Q6P5W6 O75108 O60615 D3DX78 O75107 O75081 O75082 O60616
Accessions AAC64701 AAC64702 BAA31276 BAA31277 CBX47447 CBX47448 EAW66746 EAW66747 EAW66748 EAW66749 EAW66750 EAW66751 EAW66752 O75081 AB010419 BAA29061 AB010420 BAA29062 AF052220 AAC64698 AK090985 BAG52257 AK097904 AK308355 AK314766 BAG37304 BC009554 BC047019 AAH47019 BC062624 AAH62624 BE243049 BE676580 BP282804 EU446890 ABZ92419 XM_005256323 XP_005256380 XM_006721319 XP_006721382 XM_006721320 XP_006721383 XM_011523419 XP_011521721 XR_933473 NM_005187 NP_005178 NM_175931 NP_787127
Function Functions as a transcriptional repressor. Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. Plays a role in granulocyte differentiation.
Subcellular Location Isoform 1: Nucleus, nucleolus. Note=The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm.
Tissue Specificity Widely expressed with higher expression in heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes. Expressed in hematopoietic cells (at protein level). {ECO:0000269|PubMed:15231665, ECO:0000269|PubMed:9596646, ECO:0000269|PubMed:9790752}.

ETO-2 (C-12) - sc-373691 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ETO-2 (C-12): sc-373691. Western blot analysis of ETO-2 expression in non-transfected: sc-117752 (A) and human ETO-2 transfected: sc-116819 (B) 293T whole cell lysates.

ETO-2 (D-4) - sc-166058 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ETO-2 (D-4): sc-166058. Western blot analysis of ETO-2 expression in non-transfected: sc-117752 (A) and human ETO-2 transfected: sc-116819 (B) 293T whole cell lysates.

ETO-2 (G-7) - sc-390332 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ETO-2 (G-7): sc-390332. Western blot analysis of ETO-2 expression in non-transfected: sc-117752 (A) and human ETO-2 transfected: sc-116819 (B) 293T whole cell lysates.

ETO-2 (G-20) - sc-9741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ETO-2 (G-20): sc-9741. Western blot analysis of ETO-2 expression in AML-193 (A), CCRF-CEM (B), HuT 78 (C), HL-60 (D) and MOLT-4 (E) whole cell lysates.

ETO-2 (C-20) - sc-9739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ETO-2 (C-20): sc-9739. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human tonsil showing nuclear staining.

ETO-2 (H-63) - sc-28694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ETO-2 (H-63): sc-28694. Western blot analysis of ETO-2 expression in non-transfected: sc-117752 (A) and human ETO-2 transfected: sc-116819 (B) 293T whole cell lysates.

ETO-2 (N-19) - sc-9738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ETO-2 (N-19): sc-9738. Western blot analysis of ETO-2 expression in non-transfected: sc-117752 (A) and human ETO-2 transfected: sc-116819 (B) 293T whole cell lysates.

Anti-CBFA2T3 antibody - ab129444 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CBFA2T3 antibody (ab129444) at 0.1 µg/mlLane 1 : Jurkat whole cell lysate at 50 µgLane 2 : Jurkat whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 50 µgLane 4 : HeLa whole cell lysate at 50 µg

Anti-CBFA2T3 antibody - ab167326 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CBFA2T3 antibody (ab167326) at 1 µg/mlLane 1 : CBFA2T3 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 2500

Anti-CBFA2T3 antibody - ab110823 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab110823, at 1/50 dilution, staining CBFA2T3 in paraffin-embedded Human brain tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-CBFA2T3 antibody - ab87159 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CBFA2T3 antibody (ab87159) at 1 µg/mlLane 1 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 2 : Bone Marrow (Human) Tissue Lysate - adult normal tissue Lane 3 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CBFA2T3 Antibody - LS-C306752 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CBFA2T3 Antibody (aa261-310) - LS-C118998 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using MTG16 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CBFA2T3 Antibody (N-Terminus) - LS-C29962 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-CBFA2T3 Antibody (N-Terminus) - LS-C31692 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-CBFA2T3 Antibody (aa603-653) - LS-C290275 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CBFA2T3 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from Jurkat (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-CBFA2T3 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. CBFA2T3 was also immunoprecipitated by rabbit anti-CBFA2T3 antibody BL12836, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

CBFA2T3 Antibody - H00000863-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CBFA2T3 Antibody [H00000863-B01] - analysis of CBFA2T3 expression in transfected 293T cell line by CBFA2T3 MaxPab polyclonal antibody (B01). Lane 1: CBFA2T3 transfected lysate (66.90 KDa). Lane 2: Non-transfected lysate.

CBFA2T3 Antibody - H00000863-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

CBFA2T3 Antibody - NBP1-55624 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: CBFA2T3 Antibody [NBP1-55624] - Analysis of paraffin-embedded human brain tissue, using CBFA2T3 Antibody. The picture on the right is treated with the synthesized peptide.

CBFA2T3 Antibody - NBP2-04048 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T3 (AB1) antibody produced in rabbit - AV33993 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV33993</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.0 μg/mL in cell type Jurkat

Anti-CBFA2T3 antibody produced in mouse - SAB1405563 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CBFA2T3: <B>Cat. No. SAB1405563</B>: Antibody concentration: 3 μg/mL using human esophagus tissue.

Anti-CBFA2T3 (AB2) antibody produced in rabbit - AV38578 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV38578</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 2.5 μg/mL in cell type Jurkat

CBFA2T3 antibody - N-terminal region (ARP33993_P050) - ARP33993_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CBFA2T3 antibody - N-terminal region (ARP38578_T100) - ARP38578_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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