Gene Symbol | CBFA2T3 |
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Entrez Gene | 863 |
Alt Symbol | ETO2, MTG16, MTGR2, ZMYND4 |
Species | Human |
Gene Type | protein-coding |
Description | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
Other Description | MTG8-related gene 2|MTG8-related protein 2|myeloid translocation gene 8 and 16b|myeloid translocation gene on chromosome 16 protein|protein CBFA2T3|zinc finger MYND domain-containing protein 4 |
Swissprots | O60617 Q0P5Z6 Q6P5W6 O75108 O60615 D3DX78 O75107 O75081 O75082 O60616 |
Accessions | AAC64701 AAC64702 BAA31276 BAA31277 CBX47447 CBX47448 EAW66746 EAW66747 EAW66748 EAW66749 EAW66750 EAW66751 EAW66752 O75081 AB010419 BAA29061 AB010420 BAA29062 AF052220 AAC64698 AK090985 BAG52257 AK097904 AK308355 AK314766 BAG37304 BC009554 BC047019 AAH47019 BC062624 AAH62624 BE243049 BE676580 BP282804 EU446890 ABZ92419 XM_005256323 XP_005256380 XM_006721319 XP_006721382 XM_006721320 XP_006721383 XM_011523419 XP_011521721 XR_933473 NM_005187 NP_005178 NM_175931 NP_787127 |
Function | Functions as a transcriptional repressor. Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. Plays a role in granulocyte differentiation. |
Subcellular Location | Isoform 1: Nucleus, nucleolus. Note=The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm. |
Tissue Specificity | Widely expressed with higher expression in heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes. Expressed in hematopoietic cells (at protein level). {ECO:0000269|PubMed:15231665, ECO:0000269|PubMed:9596646, ECO:0000269|PubMed:9790752}. |
Human CBFA2T3 full length protein - ab152257 from Abcam
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Human CBFA2T3 protein fragment - ab152258 from Abcam
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CBFA2T3 Antibody Blocking Peptide - LS-E12026 from LifeSpan Bioscience
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CBFA2T3 Antibody Blocking Peptide - LS-E13880 from LifeSpan Bioscience
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Recombinant Human CBFA2T3 Protein - H00000863-P01 from Novus Biologicals
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Recombinant Human CBFA2T3 Protein - H00000863-Q01 from Novus Biologicals
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CBFA2T3 - H00000863-P01-10 from Acris Antibodies
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CBFA2T3 - H00000863-P01-25 from Acris Antibodies
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CBFA2T3 - H00000863-Q01-10 from Acris Antibodies
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CBFA2T3 - H00000863-Q01-25 from Acris Antibodies
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CBFA2T3 fusion protein - ag9265 from Proteintech Group
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CBFA2T3 fusion protein - Ag9148 from Proteintech Group
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Recombinant Human Protein CBFA2T3(CBFA2T3) - CSB-YP004576HU CSB-EP004576HU CSB-BP004576HU CSB-MP004576HU from Cusabio
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CBFA2T3 (transcript variant 1) - TP312257 from Acris Antibodies
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CBFA2T3 Peptide, Human - M34GP02419H from Creative Peptides
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Protein CBFA2T3 (CBFA2T3), Recombinant Protein - MBS1080491 from MyBioSource
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CBFA2T3 Recombinant Protein Antigen - NBP2-57636PEP from Novus Biologicals
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