CBFA2T3

Gene Symbol CBFA2T3
Entrez Gene 863
Alt Symbol ETO2, MTG16, MTGR2, ZMYND4
Species Human
Gene Type protein-coding
Description core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Other Description MTG8-related gene 2|MTG8-related protein 2|myeloid translocation gene 8 and 16b|myeloid translocation gene on chromosome 16 protein|protein CBFA2T3|zinc finger MYND domain-containing protein 4
Swissprots O60617 Q0P5Z6 Q6P5W6 O75108 O60615 D3DX78 O75107 O75081 O75082 O60616
Accessions AAC64701 AAC64702 BAA31276 BAA31277 CBX47447 CBX47448 EAW66746 EAW66747 EAW66748 EAW66749 EAW66750 EAW66751 EAW66752 O75081 AB010419 BAA29061 AB010420 BAA29062 AF052220 AAC64698 AK090985 BAG52257 AK097904 AK308355 AK314766 BAG37304 BC009554 BC047019 AAH47019 BC062624 AAH62624 BE243049 BE676580 BP282804 EU446890 ABZ92419 XM_005256323 XP_005256380 XM_006721319 XP_006721382 XM_006721320 XP_006721383 XM_011523419 XP_011521721 XR_933473 NM_005187 NP_005178 NM_175931 NP_787127
Function Functions as a transcriptional repressor. Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. Plays a role in granulocyte differentiation.
Subcellular Location Isoform 1: Nucleus, nucleolus. Note=The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm.
Tissue Specificity Widely expressed with higher expression in heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes. Expressed in hematopoietic cells (at protein level). {ECO:0000269|PubMed:15231665, ECO:0000269|PubMed:9596646, ECO:0000269|PubMed:9790752}.

ETO-2 CRISPR/Cas9 KO Plasmid (h) - sc-404475 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 HDR Plasmid (h) - sc-404475-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 Double Nickase Plasmid (h) - sc-404475-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 Double Nickase Plasmid (h2) - sc-404475-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 CRISPR Activation Plasmid (h) - sc-404475-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 CRISPR Activation Plasmid (h2) - sc-404475-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 Lentiviral Activation Particles (h) - sc-404475-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 Lentiviral Activation Particles (h2) - sc-404475-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ETO-2 siRNA (h) - sc-35344 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ETO-2 shRNA Plasmid (h) - sc-35344-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ETO-2 shRNA (h) Lentiviral Particles - sc-35344-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CBFA2T3 RNAi - H00000863-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CBFA2T3 RNAi - H00000863-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU077071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5407 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5407 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12881 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12881

CBFA2T3 siRNA (Human) - CRH0608 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBFA2T3 - MBS8205508 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CBFA2T3 (NM_175931.2) - SHH255277 from Creative biogene

Category siRNA
Species Reactivities Human

CBFA2T3 shRNA Plasmid (Human) - CHH0608 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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