RBMX

Gene Symbol RBMX
Entrez Gene 27316
Alt Symbol HNRNPG, HNRPG, RBMXP1, RBMXRT, RNMX, hnRNP-G
Species Human
Gene Type protein-coding
Description RNA binding motif protein, X-linked
Other Description RNA binding motif protein, X chromosome|RNA-binding motif protein, X chromosome|glycoprotein p43|heterogeneous nuclear ribonucleoprotein G|hnRNP G
Swissprots D3DWH0 P38159 E9PG86 Q969R3 Q8N8Y7 Q5JQ67 B4E3U4
Accessions AAK58567 EAW88453 EAW88454 EAW88455 EAW88456 EAW88457 P38159 AA160187 AK091520 BAG52377 AK096015 BAC04674 AK097941 AK304573 BAG65364 AK304868 BAG65606 AK309911 AY464692 AAR28036 BC006550 AAH06550 BC007435 AAH07435 BM147410 BM993214 BU587845 BX647131 DA925805 DC337568 DQ893211 ABM84137 DQ896540 ABM87539 Z23064 CAA80599 NM_001164803 NP_001158275 NM_002139 NP_002130 NR_028476 NR_028477
Function RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single- stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the
Subcellular Location Nucleus {ECO:0000269|PubMed:19282290, ECO:0000269|PubMed:21327109}. Note=Component of ribonucleosomes. Localizes in numerous small granules in the nucleus.
Tissue Specificity Expressed strongly in oral keratinocytes, but only weakly detected in oral squamous cell carcinomas (at protein level). {ECO:0000269|PubMed:16707624}.
Top Pathways Spliceosome

RBMX overexpression lysate - LY419511 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

hnRNP G Overexpression Lysate (Native) - NBP2-10806 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: hnRNP G Overexpression Lysate (Adult Normal) [NBP2-10806] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for hnRNP G.

Panoply™ Human RBMX Knockdown Stable Cell Line - CSC-DC013082 from Creative biogene

Category Cell Line
Species Human
Search more