RBMX

Gene Symbol	RBMX
Entrez Gene	27316
Alt Symbol	HNRNPG, HNRPG, RBMXP1, RBMXRT, RNMX, hnRNP-G
Species	Human
Gene Type	protein-coding
Description	RNA binding motif protein, X-linked
Other Description	RNA binding motif protein, X chromosome|RNA-binding motif protein, X chromosome|glycoprotein p43|heterogeneous nuclear ribonucleoprotein G|hnRNP G
Swissprots	D3DWH0 P38159 E9PG86 Q969R3 Q8N8Y7 Q5JQ67 B4E3U4
Accessions	AAK58567 EAW88453 EAW88454 EAW88455 EAW88456 EAW88457 P38159 AA160187 AK091520 BAG52377 AK096015 BAC04674 AK097941 AK304573 BAG65364 AK304868 BAG65606 AK309911 AY464692 AAR28036 BC006550 AAH06550 BC007435 AAH07435 BM147410 BM993214 BU587845 BX647131 DA925805 DC337568 DQ893211 ABM84137 DQ896540 ABM87539 Z23064 CAA80599 NM_001164803 NP_001158275 NM_002139 NP_002130 NR_028476 NR_028477
Function	RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single- stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the
Subcellular Location	Nucleus {ECO:0000269|PubMed:19282290, ECO:0000269|PubMed:21327109}. Note=Component of ribonucleosomes. Localizes in numerous small granules in the nucleus.
Tissue Specificity	Expressed strongly in oral keratinocytes, but only weakly detected in oral squamous cell carcinomas (at protein level). {ECO:0000269|PubMed:16707624}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RBMX Antibody Blocking Peptide - LS-E22565 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RBMX Antibody Blocking Peptide - LS-E22564 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RBMX Blocking Peptide - 33R-10408 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RBMX fusion protein - ag1659 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human RBMX, GST-tagged - RBMX-2220H from Creative Biomart Category Protein Source E.coli Species Human

hnRNP G (M40) Peptide - BS2274P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human RNA-binding motif protein, X chromosome(RBMX) - CSB-YP019444HU CSB-EP019444HU CSB-BP019444HU CSB-MP019444HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

hnRNP G Blocking Peptide - CBP4195 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig, Zebrafish

hnRNP G Blocking Peptide - abx161406 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig, Zebrafish

hnRNP G Recombinant Protein Antigen - NBP2-34152PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RBMX-Blocking-Peptide-Center - BP21511c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RBMX-Blocking-Peptide-Center - BP21472c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RBMX Peptide, Human - M34GP13082H from Creative Peptides Category Peptide Source Synthetic. Species Human

RNA-binding motif protein, X chromosome (RBMX), Recombinant Protein - MBS965693 from MyBioSource Category Protein Prices $1,160.00, $1,160.00, $1,390.00, $1,390.00, $1,860.00, $1,860.00, $2,325.00, $2,325.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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