Gene Symbol | CLEC11A |
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Entrez Gene | 6320 |
Alt Symbol | CLECSF3, LSLCL, P47, SCGF |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 11, member A |
Other Description | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3|C-type lectin domain family 11 member A|C-type lectin superfamily member 3|lymphocyte secreted C-type lectin|lymphocyte secreted long form of C-type lectin|stem cell growth factor|stem cell growth factor; lymphocyte secreted C-type lectin |
Swissprots | B2RAD4 Q9Y240 |
Accessions | AAD26533 CAS01773 EAW71895 EAW71896 EAW71897 Q9Y240 AB009244 BAA32404 AF020044 AAC39569 AK314141 BAG36831 AY870345 AAX62798 BC005810 AAH05810 BQ014793 BT019673 AAV38479 BU615665 D86586 BAA21499 HQ448166 ADQ32647 NM_002975 NP_002966 |
Function | Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. {ECO:0000269|PubMed:11920266}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11803813}. Secreted {ECO:0000269|PubMed:11803813}. |
Tissue Specificity | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. {ECO:0000269|PubMed:11803813, ECO:0000269|PubMed:11920266, ECO:0000269|PubMed:9442024, ECO:0000269|PubMed:9705843}. |
Active SCGF beta full length protein - ab9836 from Abcam
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Human SCGF alpha full length protein - ab54145 from Abcam
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Human SCGF beta full length protein - ab54178 from Abcam
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Human SCGF full length protein - ab191715 from Abcam
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Human SCGF full length protein - ab198771 from Abcam
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SCGF Antibody Blocking Peptide - LS-E732 from LifeSpan Bioscience
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Recombinant Human SCGF beta Protein - H00006320-Q01 from Novus Biologicals
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CLEC11A-Antibody-Center-Blocking-peptide - BP11087c from Abgent, a WuXi AppTec company
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SCGF- beta recombinant protein - GTX53856 from GeneTex
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Recombinant Human SCGF-alpha/CLEC11a - 1904-SC-025 from R&D Systems
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Recombinant Human SCGF-alpha/CLEC11a, CF - 1904-SC-025/CF from R&D Systems
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SCGF / CLEC11A (SCGF-alpha) - PA125 from Acris Antibodies
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SCGF / CLEC11A (SCGF-alpha) - PA125X from Acris Antibodies
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SCGF / CLEC11A (SCGF-beta) - PA160 from Acris Antibodies
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SCGF / CLEC11A (SCGF-beta) - PA160X from Acris Antibodies
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SCGF / CLEC11A - H00006320-Q01-10 from Acris Antibodies
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SCGF / CLEC11A - H00006320-Q01-25 from Acris Antibodies
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SCGF / CLEC11A - P6147 from Acris Antibodies
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SCGF / CLEC11A - P6148 from Acris Antibodies
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SCGF alpha Recombinant Protein - 40-168 from ProSci
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CLEC11A fusion protein - Ag21365 from Proteintech Group
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Recombinant Human C-type Lectin Domain Family 11, Member A - CLEC11A-1409H from Creative Biomart
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Recombinant Human CLEC11A - CLEC11A-30960TH from Creative Biomart
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Recombinant Human CLEC11A - CLEC11A-30961TH from Creative Biomart
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Recombinant Human C-Type Lectin Domain Family 11, Member A - CLEC11A-1204H from Creative Biomart
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